Bhagawati Jahnabi, Patel Mansi, Saboo Keyur, Kumar Sunil, Acharya Sourya
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Department of Internal Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2022 Dec 31;14(12):e33170. doi: 10.7759/cureus.33170. eCollection 2022 Dec.
In Jaccoud's arthropathy (JA), classical deformities that resemble rheumatoid arthritis (RA), such as swan neck deformity and ulnar deviation, are present, but in contrast to RA, these are to passive movement and nonerosive arthritis. Similar deformities are also described in various connective tissue disorders. Mixed connective tissue disease (MCTD) characteristically has overlapping features of various connective tissue diseases (CTDs) such as systemic lupus erythematosus, systemic sclerosis, and myosotis with an association of U1RNP antibody. Approximately 60% of patients with MCTD may have deforming arthritis. We present a case of a 23-year-old male, with multiple overlapping clinical features and deforming arthritis. This case begs the question to identify various possible differentials of deforming arthritis.
在雅库病（JA）中，存在类似类风湿关节炎（RA）的典型畸形，如天鹅颈畸形和尺侧偏斜，但与RA不同的是，这些畸形对被动运动有反应且为非侵蚀性关节炎。各种结缔组织疾病中也描述了类似的畸形。混合性结缔组织病（MCTD）的特征是具有各种结缔组织疾病（CTD）的重叠特征，如系统性红斑狼疮、系统性硬化症和伴有U1RNP抗体的肌炎。大约60%的MCTD患者可能患有变形性关节炎。我们报告一例23岁男性病例，具有多种重叠的临床特征和变形性关节炎。该病例引发了识别变形性关节炎各种可能鉴别诊断的问题。
