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通过广角光学相干断层扫描测量的正常周边脉络膜厚度

NORMAL PERIPHERAL CHOROIDAL THICKNESS MEASURED BY WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY.

作者信息

Funatsu Ryoh, Sonoda Shozo, Terasaki Hiroto, Shiihara Hideki, Mihara Naohisa, Horie Juun, Sakamoto Taiji

机构信息

Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan; and.

Canon Inc., Tokyo, Japan.

出版信息

Retina. 2023 Mar 1;43(3):490-497. doi: 10.1097/IAE.0000000000003685. Epub 2023 Jan 2.

Abstract

PURPOSE

Choroidal stasis plays an important role in the pathogenesis of many conditions and leads to choroidal thickening. However, the normal peripheral choroidal thickness (PCT) pattern remains unknown. This study investigated PCT and associated factors using ultrawidefield optical coherence tomography in healthy eyes.

METHODS

This cross-sectional study included 120 healthy eyes (57 males; age, 52.0 ± 20.5 years). We used choroidal thickness maps created by ultrawidefield optical coherence tomography (viewing angle, 200°) with real-shape correction. The peripheral area was defined from 60° to 100° and further separated vertically and horizontally. The PCT and the correlations between PCT and subjects' characteristics were examined.

RESULTS

The PCT were 227.1 ± 57.0 µ m, 199.6 ± 53.9 µ m, 196.6 ± 57.1 µ m, and 148.0 ± 38.2 µ m in supratemporal, infratemporal, supranasal, and infranasal areas, respectively. The thickest peripheral sector was most frequently observed in supratemporal (69.2%). The PCT negatively correlated with age in all regions ( P -values < 0.001) and axial length in supratemporal, supranasal, and infranasal areas ( P -values ≤ 0.003). The temporal PCT was thicker on the side contiguous with the posterior pole Haller's vessels ( P -values ≤ 0.020).

CONCLUSION

The PCT is associated with age, axial length, and the running pattern of Haller's vessels.

摘要

目的

脉络膜血流淤滞在许多疾病的发病机制中起重要作用,并导致脉络膜增厚。然而,正常的周边脉络膜厚度(PCT)模式仍不清楚。本研究使用超广角光学相干断层扫描技术对健康眼的PCT及相关因素进行了研究。

方法

本横断面研究纳入了120只健康眼(57例男性;年龄52.0±20.5岁)。我们使用了经真实形状校正的超广角光学相干断层扫描(视角200°)创建的脉络膜厚度图。周边区域定义为60°至100°,并进一步垂直和水平划分。检查了PCT以及PCT与受试者特征之间的相关性。

结果

颞上、颞下、鼻上和鼻下区域的PCT分别为227.1±57.0μm、199.6±53.9μm、196.6±57.1μm和148.0±38.2μm。最常观察到的周边最厚扇形区域位于颞上(69.2%)。所有区域的PCT均与年龄呈负相关(P值<0.001),颞上、鼻上和鼻下区域的PCT与眼轴长度呈负相关(P值≤0.003)。颞侧PCT在与后极部哈勒氏血管相邻的一侧更厚(P值≤0.020)。

结论

PCT与年龄、眼轴长度和哈勒氏血管的走行模式有关。

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