Pusterla Nicola
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA.
Vet Clin North Am Equine Pract. 2023 Apr;39(1):55-71. doi: 10.1016/j.cveq.2022.11.008. Epub 2022 Nov 21.
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In equids, equine coronavirus has been associated with diarrhea in foals and lethargy, fever, anorexia, and occasional gastrointestinal signs in adult horses. Although horses seem to be susceptible to the human severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) based on the high homology to the ACE-2 receptor, they seem to be incidental hosts because of occasional SARS-CoV-2 spillover from humans. However, until more clinical and seroepidemiological data are available, it remains important to monitor equids for possible transmission from humans with clinical or asymptomatic COVID-19.
冠状病毒是一组相关的RNA病毒，可导致哺乳动物和鸟类患病。在马科动物中，马冠状病毒与幼驹腹泻以及成年马的嗜睡、发热、厌食和偶尔的胃肠道症状有关。尽管基于与ACE-2受体的高度同源性，马似乎对人类严重急性呼吸综合征冠状病毒2（SARS-CoV-2）易感，但由于偶尔会出现SARS-CoV-2从人类传播过来的情况，它们似乎只是偶然宿主。然而，在获得更多临床和血清流行病学数据之前，监测马科动物是否可能从患有临床型或无症状型COVID-19的人类那里感染病毒仍然很重要。
