长时间工作及夜班工作时长与新发糖尿病的关系：一项台湾地区的回顾性队列研究
Relationship of long working hours and night shift working hours with incident diabetes: a retrospective cohort study in Taiwan.
作者信息
Chen Wan-Chin, Yang Hsiao-Yu
机构信息
Department of Family Medicine, Changhua Christian Hospital, No. 135, Nanxiao St., Changhua City, Taiwan; Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, No. 17 Xuzhou Road, Zhongzheng Dist., Taipei, Taiwan.
Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, No. 17 Xuzhou Road, Zhongzheng Dist., Taipei, Taiwan; Department of Environmental and Occupational Medicine, National Taiwan University Hospital, No. 1, Changde St., Zhongzheng Dist., Taipei, Taiwan; Department of Public Health, National Taiwan University College of Public Health, No. 17 Xuzhou Road, Zhongzheng Dist., Taipei, Taiwan.
出版信息
Ann Epidemiol. 2023 Apr;80:9-15. doi: 10.1016/j.annepidem.2023.01.013. Epub 2023 Feb 3.
PURPOSE
The relationship among long working hours, night shift working hours, and diabetes is still unclear. We aimed to evaluate the association of long working hours and night shift working hours with diabetes among health care workers.
METHODS
We conducted a retrospective cohort study among health care workers in a tertiary medical center in Taiwan from 2002 to 2019. We compared the risk of diabetes among tertiles of total working hours (35-41, 42-45, and ≥46 h per week) and evaluated the relationship between long working hours and diabetes risk. We divided participants into three work patterns: day work only, evening shift workers, and night shift workers. In night shift workers, we further evaluated night shift working hours and incident diabetes using tertiles of night shift working hours (<17, 17-45, and ≥46 h per month). We estimated hazard ratios and 95% confidence intervals for incident diabetes using multivariable Cox proportional hazards models.
RESULTS
The study included 7081 participants. There were 301 incident cases of diabetes during 52,454 person-years. The adjusted hazard ratio (95% confidence interval) for participants who worked greater than or equal to 46 working hours per week was 3.45 (1.27, 9.39) compared with those who worked 35-41 hours. Compared with night shift workers who worked less than 17 h, the adjusted hazard ratios (95% confidence interval) for those who worked 17-45 and ≥46 night shift working hours per month were 2.26 (1.08, 4.75) and 2.60 (1.27, 5.33), respectively.
CONCLUSIONS
Long working hours and night shift working hours increased the risk of diabetes.
目的
长时间工作、夜班工作时长与糖尿病之间的关系仍不明确。我们旨在评估医护人员中长时间工作和夜班工作时长与糖尿病之间的关联。
方法
我们对2002年至2019年台湾一家三级医疗中心的医护人员进行了一项回顾性队列研究。我们比较了总工作时长三分位数（每周35 - 41、42 - 45以及≥46小时）人群中糖尿病的风险，并评估了长时间工作与糖尿病风险之间的关系。我们将参与者分为三种工作模式：仅日班工作者、晚班工作者和夜班工作者。在夜班工作者中，我们进一步使用夜班工作时长三分位数（每月<17、17 - 45以及≥46小时）评估夜班工作时长与糖尿病发病情况。我们使用多变量Cox比例风险模型估计糖尿病发病的风险比和95%置信区间。
结果
该研究纳入了7081名参与者。在52454人年期间有301例糖尿病发病病例。每周工作时长大于或等于46小时的参与者与每周工作35 - 41小时的参与者相比，调整后的风险比（95%置信区间）为3.45（1.27，9.39）。与每月夜班工作时长少于17小时的夜班工作者相比，每月夜班工作时长为17 - 45小时和≥46小时的参与者调整后的风险比（95%置信区间）分别为2.26（1.08，4.75）和2.60（1.27，5.33）。
结论
长时间工作和夜班工作时长会增加患糖尿病的风险。
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