针对耐甲氧西林金黄色葡萄球菌引起的实验性心内膜炎的单一抗生素疗法和联合抗生素疗法
Single- and combination-antibiotic therapy for experimental endocarditis caused by methicillin-resistant Staphylococcus aureus.
作者信息
Rodríguez A, Vicente M V, Olay T
机构信息
Instituto de Farmacología Española, Madrid, Spain.
出版信息
Antimicrob Agents Chemother. 1987 Sep;31(9):1444-5. doi: 10.1128/AAC.31.9.1444.
Abstract
The efficacy of fosfomycin in combination with vancomycin or gentamicin was evaluated in experimental endocarditis caused by methicillin-resistant Staphylococcus aureus. After 5 days of therapy, both combinations proved to be highly effective since all rabbits had sterile vegetations.
摘要
在耐甲氧西林金黄色葡萄球菌引起的实验性心内膜炎中，对磷霉素与万古霉素或庆大霉素联合使用的疗效进行了评估。治疗5天后，两种联合用药均显示出高效，因为所有兔子的赘生物均无菌。
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本文引用的文献
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Experimental endocarditis caused by Streptococcus sanguis: single and combined antibiotic therapy.血链球菌引起的实验性心内膜炎：单一及联合抗生素治疗
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In vitro activities of teichomycin, fusidic acid, flucloxacillin, fosfomycin, and vancomycin against methicillin-resistant Staphylococcus aureus.替考拉宁、夫西地酸、氟氯西林、磷霉素和万古霉素对耐甲氧西林金黄色葡萄球菌的体外活性。
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In vitro activity of fosfomycin, alone and in combination, against methicillin-resistant Staphylococcus aureus.磷霉素单独及联合使用时对耐甲氧西林金黄色葡萄球菌的体外活性。
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