Lean Fabian Z X, Johnson Nicholas
Pathology and Animal Sciences Department, Animal and Plant Health Agency, Woodham Lane, Addlestone, KT15 3NB, UK.
Vector Borne Diseases, Virology Department, Animal and Plant Health Agency, Woodham Lane, Addlestone, KT15 3NB, UK.
J Med Microbiol. 2022 Dec;72(12). doi: 10.1099/jmm.0.001619.
Rift Valley fever (RVF) is caused by infection with Rift Valley fever virus (RVFV), a mosquito-borne RNA virus that affects both humans and livestock species. Humans can also acquire infection from contact with infected animals and contaminated bodily fluid. Veterinary vaccines are available for use in livestock, but no vaccines have been approved for humans to date. The virus is currently endemic in most sub-Saharan regions of Africa but numerous incursions into Middle Eastern countries and islands in the Indian Ocean, such as Mayotte (an overseas Department of France), have occurred in the past decade. The risk of further geographical expansion is high and therefore additional investigation is warranted to better understand disease transmission and pathogenic mechanisms to develop threat mitigation strategies.
裂谷热（RVF）由感染裂谷热病毒（RVFV）引起，RVFV是一种通过蚊子传播的RNA病毒，可感染人类和家畜。人类也可能因接触受感染动物和受污染的体液而感染。有兽用疫苗可用于家畜，但目前尚无获批用于人类的疫苗。该病毒目前在非洲撒哈拉以南的大部分地区流行，但在过去十年中，曾多次传入中东国家和印度洋岛屿，如马约特岛（法国的一个海外省）。进一步地理扩张的风险很高，因此有必要进行更多调查，以更好地了解疾病传播和致病机制，从而制定减轻威胁的策略。
