Li Zhen, Long Lingbo, Jin Xu, Li Yang, Wu Qiong, Chen Xingyong, Geng Zhaoyu, Zhang Cheng
Department of Animal Science, College of Animal Science and Technology, Anhui Agricultural University, Hefei, China.
Front Vet Sci. 2023 Jan 24;10:1107798. doi: 10.3389/fvets.2023.1107798. eCollection 2023.
This study investigated the effects of on the growth performance, meat quality and intestinal health of broilers. A total of 800 one-day-old male Arbor Acres broilers were randomly assigned to two groups with 16 replicates of 25 broilers per group and fed with a basal diet (CON) or a basal diet supplemented with 1.5 × 10 cfu/kg and 5 × 10 cfu/kg at 1-21 d and 22-42 d, respectively (CB). The results indicated that significantly increased the final body weight, average daily gain at 1-42 d in the growth performance of broilers ( < 0.05). Moreover, significantly increased value and pH value of breast meat but reduced the drip loss and shear force ( < 0.05). Regarding serum antioxidant indices, significantly increased the total superoxide dismutase (T-SOD) and total antioxidative capacity activities and reduced the malondialdehyde content ( < 0.05). Furthermore, the broilers in the CB demonstrated an increase in jejunal lipase and trypsin activities, villus height (VH) and VH-to-crypt depth ratio at 42 d compared with those in the CON ( < 0.05). also upregulated the intestinal mRNA levels of zonula occludens-1, nuclear factor erythroid 2-related factor 2 ), and interleukin-10 in the jejunal mucosa ( < 0.05), but it downregulated the mRNA levels of nuclear factor kappa B (κ) and tumor necrosis factor-α ( < 0.05). These results indicate that can improve the growth performance and meat quality of broilers. In particular, can improve the intestinal health of broilers, which is likely to be related to the activation of the Nrf2 signaling pathway and inhibition of the NF-κB signaling pathway.
本研究调查了[具体物质]对肉鸡生长性能、肉质和肠道健康的影响。总共800只1日龄雄性艾维茵肉鸡被随机分为两组,每组16个重复,每个重复25只肉鸡,分别在1 - 21日龄和22 - 42日龄时饲喂基础日粮(CON)或添加1.5×10⁸ cfu/kg[具体物质1]和5×10⁸ cfu/kg[具体物质2]的基础日粮(CB)。结果表明,[具体物质]显著提高了肉鸡生长性能中1 - 42日龄的末体重和平均日增重(P < 0.05)。此外,[具体物质]显著提高了胸肉的亮度值和pH值,但降低了滴水损失和剪切力(P < 0.05)。关于血清抗氧化指标,[具体物质]显著提高了总超氧化物歧化酶(T - SOD)和总抗氧化能力活性,并降低了丙二醛含量(P < 0.05)。此外,与CON组相比,CB组肉鸡在42日龄时空肠脂肪酶和胰蛋白酶活性、绒毛高度(VH)以及VH与隐窝深度比值均有所增加(P < 0.05)。[具体物质]还上调了空肠黏膜中紧密连接蛋白1、核因子红细胞2相关因子2(Nrf2)、[具体物质3]和白细胞介素10的肠道mRNA水平(P < 0.05),但下调了核因子κB(NF - κB)和肿瘤坏死因子 - α的mRNA水平(P < 0.05)。这些结果表明,[具体物质]可以改善肉鸡的生长性能和肉质。特别是,[具体物质]可以改善肉鸡的肠道健康,这可能与激活Nrf2信号通路和抑制NF - κB信号通路有关。