Gassenmaier Sebastian, Warm Verena, Nickel Dominik, Weiland Elisabeth, Herrmann Judith, Almansour Haidara, Wessling Daniel, Afat Saif
Department of Diagnostic and Interventional Radiology, Eberhard Karls University Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, Germany.
Institute for Pathology and Neuropathology, University Hospital of Tuebingen, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.
Cancers (Basel). 2023 Jan 18;15(3):578. doi: 10.3390/cancers15030578.
Thin-slice prostate MRI might be beneficial for prostate cancer diagnostics. However, prolongation of acquisition time is a major drawback of thin-slice imaging. Therefore, the purpose of this study was to investigate the impact of a thin-slice deep learning accelerated T2-weighted (w) TSE imaging sequence (T2) of the prostate as compared to conventional T2w TSE imaging (T2).
Thirty patients were included in this prospective study at one university center after obtaining written informed consent. T2 (3 mm slice thickness) was acquired first in three orthogonal planes followed by thin-slice T2 (2 mm slice thickness) in axial plane. Acquisition time of axial conventional T2 was 4:12 min compared to 4:37 min for T2. Imaging datasets were evaluated by two radiologists using a Likert-scale ranging from 1-4, with 4 being the best regarding the following parameters: sharpness, lesion detectability, artifacts, overall image quality, and diagnostic confidence. Furthermore, preference of T2 versus T2 was evaluated.
The mean patient age was 68 ± 8 years. Sharpness of images and lesion detectability were rated better in T2 with a median of 4 versus a median of 3 in T2 ( < 0.001 for both readers). Image noise was evaluated to be significantly worse in T2 as compared to T2 ( < 0.001 and = 0.021, respectively). Overall image quality was also evaluated to be superior in T2 versus T2 with a median of 4 versus 3 ( < 0.001 for both readers). Both readers chose T2 in 29 cases as their preference.
Thin-slice T2 of the prostate provides a significant improvement of image quality without significant prolongation of acquisition time.
薄层前列腺MRI可能有助于前列腺癌的诊断。然而，采集时间延长是薄层成像的一个主要缺点。因此，本研究的目的是探讨前列腺薄层深度学习加速T2加权（w）TSE成像序列（T2）与传统T2w TSE成像（T2）相比的影响。
在一所大学中心，30名患者在获得书面知情同意后被纳入这项前瞻性研究。首先在三个正交平面上采集T2（层厚3mm），然后在轴向平面上采集薄层T2（层厚2mm）。轴向传统T2的采集时间为4:12分钟，而T2为4:37分钟。两名放射科医生使用1-4的李克特量表对成像数据集进行评估，4表示在以下参数方面最佳：清晰度、病变可检测性、伪影、整体图像质量和诊断信心。此外，还评估了对T2和T2的偏好。
患者平均年龄为68±8岁。T2图像的清晰度和病变可检测性评分更高，中位数为4，而T2为3（两位读者的P均<0.001）。与T2相比，T2的图像噪声被评估为明显更差（分别为P<0.001和P = 0.021）。T2的整体图像质量也被评估为优于T2，中位数为4对3（两位读者的P均<0.001）。两位读者在29例中都选择T2作为他们的偏好。
前列腺薄层T2在不显著延长采集时间的情况下显著提高了图像质量。
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