Department of Botany, Faculty of Science, University of Khartoum, Khartoum P.O. Box 321, Sudan.
Department of Biology, Science Faculty, Selcuk University, 42130 Konya, Turkey.
Molecules. 2023 Jan 19;28(3):1005. doi: 10.3390/molecules28031005.
Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and enzyme inhibitory activities of EO extracted from the fruit of (Siebold and Zucc.) Endl. (family Cupressaceae), root of (Benth.) Veldkampis (family Poaceae) and aerial part of Poir (family Lamiaceae). The fruit of contained only monoterpenes, mainly hydrogenated ones, with α-pinene (69.07%) as the major component. Oxygenated sesquiterpenes comprised the highest content of the root EO with cedr-8-en-15-ol (28.69%) as the major constituent while aerial parts of contained both monoterpenes and sesquiterpenes and the oxygenated monoterpene lavandulol (26.56%) as dominant compounds. The EO of the root of significantly displayed ( < 0.05) the highest anti-DPPH radical, Fe- and Cu-reducing and metal-chelating activities, while that of fruit significantly exerted ( < 0.05) the best anti-ABTS radical and total antioxidant activity. The two EOs significantly exhibited ( < 0.05) the highest anti-acetylcholinesterase and -butyrylcholinesterase activities, respectively, while EO of was the only oil to show a considerable inhibitory effect against the tyrosinase and α-glucosidase enzymes. In conclusion, EOs from these three plants could be natural agents with promising functional properties for food, cosmetics, and pharmaceutical applications.
一般来说，关于在苏丹自然生长的芳香植物的精油（EOs）的成分，最终的生物活性，数据很少。本研究旨在确定从 （Siebold and Zucc.）Endl. 的果实（柏科）、（Benth.）Veldkampis 的根（禾本科）和 （Poir）的地上部分（唇形科）提取的精油的化学成分、抗氧化和酶抑制活性。 的果实仅含有单萜类化合物，主要是氢化单萜类化合物，其中α-蒎烯（69.07%）为主要成分。氧化倍半萜烯是 根油中含量最高的，其中 Cedr-8-en-15-ol（28.69%）为主要成分，而 的地上部分则同时含有单萜类和倍半萜类化合物，其中含氧单萜类化合物 Lavandulol（26.56%）为主要成分。 的根油表现出（<0.05）最高的抗 DPPH 自由基、Fe 和 Cu 还原以及金属螯合活性，而 的果实油则表现出（<0.05）最强的抗 ABTS 自由基和总抗氧化活性。两种精油均表现出（<0.05）最高的抗乙酰胆碱酯酶和 -丁酰胆碱酯酶活性，而 的精油是唯一对酪氨酸酶和α-葡萄糖苷酶具有显著抑制作用的油。总之，这三种植物的 EOs 可能是具有食品、化妆品和制药应用前景的天然功能特性的天然剂。
