School of Natural Resources and Environmental Science, Kangwon National University, Chuncheon, Gangwon-do 24341, Republic of Korea.
Department of Botany, Kongunadu Arts and Science College, Coimbatore 641029, Tamil Nadu, India.
Molecules. 2023 Jan 23;28(3):1131. doi: 10.3390/molecules28031131.
L. is distributed throughout the world and it is an important medicinal plant in Korea to treat various human diseases. Recently, has also been considered to be an effective ethnobotanical drug against COVID-19. contains an appreciable amount of essential oil with different biological properties. However, the composition of essential oils in aromatic plants can be varied depending on several factors, including geographic, genetic, ecological, etc. Hence, the present study aimed to investigate the chemical diversity of essential oils of Korean collected from different locations in Korea by multivariate analysis. For this purpose, the seeds of were collected from 112 different locations in Korea and were grown under the same environmental conditions. Except for nine individuals which decayed during the cultivation, essential oils were isolated from the aerial parts of 103 individuals (AEOs) using the steam distillation extraction method, and their chemical compositions were determined by GC-MS analysis. Furthermore, a multivariate analysis was performed to distinguish the difference between 103 individuals of based on their essential oil compositions. The yield of essential oils ranged from 0.04 to 1.09% (/). Based on the GC-MS data, individuals were grouped into six chemotypes such as artemisia ketone, camphor, β-cubebene, eucalyptol, α-pinene, and β-selinene. The multivariate analysis results revealed that Korean could be largely grouped into three clusters such as artemisia ketone, eucalyptol, and β-selinene. Among 35 components selected for principal component analysis (PCA), PC1, PC2, and PC3 accounted for 82.55%, 8.74%, and 3.62%, respectively. Although all individuals of were cultivated under the same environmental conditions, there is an intraspecific chemical diversity that exists within Korean native species.
L. 分布于世界各地，是韩国治疗各种人类疾病的重要药用植物。最近，也被认为是对抗 COVID-19 的有效民族植物药物。 含有相当数量的具有不同生物特性的精油。然而，芳香植物中的精油组成可能因地理、遗传、生态等多种因素而有所不同。因此，本研究旨在通过多元分析研究韩国 不同产地精油的化学多样性。为此，从韩国 112 个不同地点采集 种子，并在相同的环境条件下种植。除了 9 株在培养过程中腐烂的个体外，使用水蒸气蒸馏提取法从 103 株个体的地上部分分离出精油（AEOs），并通过 GC-MS 分析确定其化学成分。此外，还进行了多元分析，以区分基于精油组成的 103 个个体之间的差异。 精油的产率范围为 0.04-1.09% (/). 根据 GC-MS 数据，将 个体分为 6 种化学型，如蒿酮、樟脑、β-蒈烯、桉油醇、α-蒎烯和β-瑟林烯。多元分析结果表明，韩国 可以大致分为 3 个聚类，如蒿酮、桉油醇和β-瑟林烯。在用于主成分分析（PCA）的 35 个选定成分中，PC1、PC2 和 PC3 分别占 82.55%、8.74%和 3.62%。尽管所有 的个体都是在相同的环境条件下种植的，但韩国本土种内存在种内化学多样性。
