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人参治疗癌症潜力的最新研究进展:“生命之泉”。

An Update on the Therapeutic Anticancer Potential of L.: "Elixir of Life".

机构信息

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Alquwayiyah 11971, Saudi Arabia.

Clinical Biochemistry Unit, Department of Pathology, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia.

出版信息

Molecules. 2023 Jan 25;28(3):1193. doi: 10.3390/molecules28031193.

Abstract

In most cases, cancer develops due to abnormal cell growth and subsequent tumour formation. Due to significant constraints with current treatments, natural compounds are being explored as potential alternatives. There are now around 30 natural compounds under clinical trials for the treatment of cancer. Tulsi, or Holy Basil, of the genus Ocimum, is one of the most widely available and cost-effective medicinal plants. In India, the tulsi plant has deep religious and medicinal significance. Tulsi essential oil contains a valuable source of bioactive compounds, such as camphor, eucalyptol, eugenol, alpha-bisabolene, beta-bisabolene, and beta-caryophyllene. These compounds are proposed to be responsible for the antimicrobial properties of the leaf extracts. The anticancer effects of tulsi ( L.) have earned it the title of "queen of herbs" and "Elixir of Life" in Ayurvedic treatment. Tulsi leaves, which have high concentrations of eugenol, have been shown to have anticancer properties. In a various cancers, eugenol exerts its antitumour effects through a number of different mechanisms. In light of this, the current review focuses on the anticancer benefits of tulsi and its primary phytoconstituent, eugenol, as apotential therapeutic agent against a wide range of cancer types. In recent years, tulsi has gained popularity due to its anticancer properties. In ongoing clinical trials, a number of tulsi plant compounds are being evaluated for their potential anticancer effects. This article discusses anticancer, chemopreventive, and antioxidant effects of tulsi.

摘要

在大多数情况下,癌症是由于细胞异常生长和随后的肿瘤形成引起的。由于目前治疗方法存在重大限制,因此正在探索天然化合物作为潜在替代品。目前约有 30 种天然化合物正在临床试验中用于癌症治疗。罗勒,或神圣罗勒,属于罗勒属,是最广泛可用和最具成本效益的药用植物之一。在印度,罗勒植物具有深厚的宗教和药用意义。罗勒精油含有有价值的生物活性化合物来源,如樟脑、桉树脑、丁香酚、α- 大根香叶烯、β-大根香叶烯和β-石竹烯。这些化合物被认为是叶提取物具有抗菌特性的原因。罗勒(L.)的抗癌作用使它在印度阿育吠陀治疗中获得了“草药皇后”和“生命之饮”的称号。罗勒叶含有高浓度的丁香酚,已被证明具有抗癌特性。在各种癌症中,丁香酚通过多种不同的机制发挥其抗肿瘤作用。有鉴于此,目前的综述重点介绍了罗勒及其主要植物成分丁香酚作为治疗多种癌症类型的潜在治疗剂的抗癌益处。近年来,罗勒因其抗癌特性而受到关注。在正在进行的临床试验中,正在评估多种罗勒植物化合物的潜在抗癌作用。本文讨论了罗勒的抗癌、化学预防和抗氧化作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7a6/9919305/2f00afcfbc9f/molecules-28-01193-g001.jpg

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