Department of Computing and Informatics, Bournemouth University, Bournemouth BH12 5BB, UK.
Sensors (Basel). 2023 Jan 28;23(3):1439. doi: 10.3390/s23031439.
Chronic obstructive pulmonary disease (COPD) concerns the serious decline of human lung functions. These have emerged as one of the most concerning health conditions over the last two decades, after cancer around the world. The early diagnosis of COPD, particularly of lung function degradation, together with monitoring the condition by physicians, and predicting the likelihood of exacerbation events in individual patients, remains an important challenge to overcome. The requirements for achieving scalable deployments of data-driven methods using artificial intelligence for meeting such a challenge in modern COPD healthcare have become of paramount and critical importance. In this study, we have established the experimental foundations for acquiring and indeed generating biomedical observation data, for good performance signal analysis and machine learning that will lead us to the intelligent diagnosis and monitoring of COPD conditions for individual patients. Further, we investigated on the multi-resolution analysis and compression of lung audio signals, while we performed their machine classification under two distinct experiments. These respectively refer to conditions involving (1) "Healthy" or "COPD" and (2) "Healthy", "COPD", or "Pneumonia" classes. Signal reconstruction with the extracted features for machine learning and testing was also performed for securing the integrity of the original audio recordings. These showed high levels of accuracy together with the performances of the selected machine learning-based classifiers using diverse metrics. Our study shows promising levels of accuracy in classifying Healthy and COPD and also Healthy, COPD, and Pneumonia conditions. Further work in this study will be imminently extended to new experiments using multi-modal sensing hardware and data fusion techniques for the development of the next generation diagnosis systems for COPD healthcare of the future.
慢性阻塞性肺疾病(COPD)涉及人类肺功能的严重下降。在过去的二十年中,COPD 已成为全球仅次于癌症的最令人关注的健康问题之一。COPD 的早期诊断,特别是肺功能下降的诊断,以及医生对病情的监测和预测个体患者恶化事件的可能性,仍然是一个需要克服的重要挑战。为了实现使用人工智能的数据驱动方法的可扩展部署,以应对现代 COPD 医疗保健中的这一挑战,满足相关需求已变得至关重要。在这项研究中,我们为获取和生成生物医学观察数据奠定了实验基础,以便进行良好的性能信号分析和机器学习,从而实现对 COPD 患者病情的智能诊断和监测。此外,我们还研究了肺部音频信号的多分辨率分析和压缩,同时在两个不同的实验中对其进行了机器分类。这分别涉及(1)“健康”或“COPD”以及(2)“健康”、“COPD”或“肺炎”类别。还对提取特征进行信号重建,用于机器学习和测试,以确保原始录音的完整性。这些结果显示了使用不同指标的基于机器学习的分类器的高度准确性和性能。我们的研究表明,在分类健康和 COPD 以及健康、COPD 和肺炎方面具有有前景的准确性水平。在这项研究中,我们将立即扩展到使用多模态传感硬件和数据融合技术的新实验,以开发未来 COPD 医疗保健的下一代诊断系统。