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人参对人体血液中酒精清除率的影响。

Effects of Panax ginseng on blood alcohol clearance in man.

作者信息

Lee F C, Ko J H, Park J K, Lee J S

机构信息

Korea Ginseng & Tobacco Research Institute, Daejeon.

出版信息

Clin Exp Pharmacol Physiol. 1987 Jun;14(6):543-6. doi: 10.1111/j.1440-1681.1987.tb01510.x.

DOI:10.1111/j.1440-1681.1987.tb01510.x
PMID:3677487
Abstract
  1. Fourteen healthy male volunteers were studied to assess the effects of Panax ginseng on blood alcohol clearance, utilizing each subject as his own control. 2. At 40 min after the last drink, the blood alcohol level in the test group receiving ginseng extract (3 g/65 kg body weight) along with alcohol (72 g/65 kg body weight) was about 35% lower than their control values. 3. When the blood alcohol level was compared on individual bases, alcohol concentrations in 10 out of 14 test subjects ranged from 32 to 51% lower than their control values. 4. These results demonstrate that P. ginseng extract enhances blood alcohol clearance in man.
摘要
  1. 对14名健康男性志愿者进行了研究,以评估人参对血液酒精清除率的影响,每个受试者都作为自己的对照。2. 在最后一次饮酒后40分钟,接受人参提取物(3克/65千克体重)和酒精(72克/65千克体重)的试验组血液酒精水平比其对照值低约35%。3. 当基于个体比较血液酒精水平时,14名试验对象中有10人的酒精浓度比其对照值低32%至51%。4. 这些结果表明人参提取物可提高人体的血液酒精清除率。

相似文献

1
Effects of Panax ginseng on blood alcohol clearance in man.人参对人体血液中酒精清除率的影响。
Clin Exp Pharmacol Physiol. 1987 Jun;14(6):543-6. doi: 10.1111/j.1440-1681.1987.tb01510.x.
2
Effect of ginseng on plasma levels of ethanol in the rat.人参对大鼠血浆乙醇水平的影响。
Planta Med. 1993 Feb;59(1):17-9. doi: 10.1055/s-2006-959595.
3
Ethanol extraction preparation of American ginseng (Panax quinquefolius L) and Korean red ginseng (Panax ginseng C.A. Meyer): differential effects on postprandial insulinemia in healthy individuals.乙醇提取西洋参(Panax quinquefolius L)和红参(Panax ginseng C.A. Meyer)的制备:对健康个体餐后胰岛素血症的影响差异。
J Ethnopharmacol. 2015 Jan 15;159:55-61. doi: 10.1016/j.jep.2014.10.057. Epub 2014 Nov 4.
4
Red ginseng relieves the effects of alcohol consumption and hangover symptoms in healthy men: a randomized crossover study.红参可缓解健康男性饮酒和宿醉症状:一项随机交叉研究。
Food Funct. 2014 Mar;5(3):528-34. doi: 10.1039/c3fo60481k.
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Panax ginseng extract improves the scopolamine-induced disruption of 8-arm radial maze performance in rats.人参提取物可改善东莨菪碱诱导的大鼠八臂辐射状迷宫行为障碍。
Biol Pharm Bull. 1995 Oct;18(10):1439-42. doi: 10.1248/bpb.18.1439.
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[Optimization of dissolution process for superfine grinding technology on total saponins of Panax ginseng fibrous root by response surface methodology].[响应面法优化超细粉碎技术对人参须根总皂苷的溶出工艺]
Zhong Yao Cai. 2014 Mar;37(3):494-8.
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American ginseng (Panax quinquefolius L.) attenuates postprandial glycemia in a time-dependent but not dose-dependent manner in healthy individuals.美国人参(西洋参,Panax quinquefolius L.)对健康个体餐后血糖的降低作用呈时间依赖性,但不呈剂量依赖性。
Am J Clin Nutr. 2001 Apr;73(4):753-8. doi: 10.1093/ajcn/73.4.753.
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Effects of aqueous extracts from Panax ginseng and Hippophae rhamnoides on acute alcohol intoxication: An experimental study using mouse model.人参和沙棘水提取物对急性酒精中毒的影响:一项使用小鼠模型的实验研究。
J Ethnopharmacol. 2016 Nov 4;192:67-73. doi: 10.1016/j.jep.2016.06.063. Epub 2016 Jul 1.
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Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained 'mentally demanding' tasks.在持续进行“精神高度集中”任务期间,与葡萄糖一起或不与葡萄糖一起服用人参对血糖水平和认知表现的影响。
J Psychopharmacol. 2006 Nov;20(6):771-81. doi: 10.1177/0269881106061516. Epub 2006 Jan 9.
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Modulation of endothelial function by Korean red ginseng (Panax ginseng C.A. Meyer) and its components in healthy individuals: a randomized controlled trial.韩国红参(人参C.A. 迈耶)及其成分对健康个体内皮功能的调节作用:一项随机对照试验。
Cardiovasc Ther. 2014 Aug;32(4):163-9. doi: 10.1111/1755-5922.12077.

引用本文的文献

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Ethnopharmacological Applications Targeting Alcohol Abuse: Overview and Outlook.针对酒精滥用的民族药理学应用:综述与展望
Front Pharmacol. 2020 Feb 14;10:1593. doi: 10.3389/fphar.2019.01593. eCollection 2019.
2
Ginseng ( Meyer) Oligopeptides Protect Against Binge Drinking-Induced Liver Damage through Inhibiting Oxidative Stress and Inflammation in Rats.人参(Meyer)低聚肽通过抑制氧化应激和炎症来防止大鼠 binge drinking 诱导的肝损伤。
Nutrients. 2018 Nov 4;10(11):1665. doi: 10.3390/nu10111665.
3
Safety and tolerability of Panax ginseng root extract: a randomized, placebo-controlled, clinical trial in healthy Korean volunteers.
人参根提取物的安全性和耐受性:一项在健康韩国志愿者中进行的随机、安慰剂对照、临床试验。
J Altern Complement Med. 2012 Nov;18(11):1061-9. doi: 10.1089/acm.2011.0591. Epub 2012 Aug 21.
4
Ginseng, the root of Panax ginseng C.A. Meyer, protects ethanol-induced gastric damages in rat through the induction of cytoprotective heat-shock protein 27.人参,即五加科人参的根,通过诱导具有细胞保护作用的热休克蛋白27,对大鼠乙醇诱导的胃损伤起到保护作用。
Dig Dis Sci. 2008 Mar;53(3):606-13. doi: 10.1007/s10620-007-9946-6. Epub 2007 Sep 1.
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Herb-drug interactions: a literature review.草药-药物相互作用:文献综述。
Drugs. 2005;65(9):1239-82. doi: 10.2165/00003495-200565090-00005.
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Panax ginseng: a systematic review of adverse effects and drug interactions.人参:不良反应与药物相互作用的系统评价
Drug Saf. 2002;25(5):323-44. doi: 10.2165/00002018-200225050-00003.
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Drugs. 2001;61(15):2163-75. doi: 10.2165/00003495-200161150-00002.
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Herb-drug interactions: review and assessment of report reliability.草药-药物相互作用:报告可靠性的综述与评估
Br J Clin Pharmacol. 2001 Nov;52(5):587-95. doi: 10.1046/j.0306-5251.2001.01469.x.