J Am Pharm Assoc (2003). 2023 May-Jun;63(3):720-724. doi: 10.1016/j.japh.2023.01.003. Epub 2023 Jan 11.
The coronavirus disease 2019 (COVID-19) pandemic has elicited many health concerns, including the impact of the infection and vaccine on reproductive health. Although robust evidence demonstrates the safety of all available COVID-19 vaccines, misinformation and disinformation related to the vaccine continue to circulate. As accessible and essential health care workers, it is crucial that pharmacists are informed of the evidence related to effects of the COVID-19 infection and vaccinations on reproductive health care. Menstrual cycle changes have been noted owing to COVID-19 infection, pandemic stress, and COVID-19 vaccination. COVID-19 infection and vaccination have not been shown to influence female fertility, pregnancy rates, and lactation. The use of exogenous estrogen may further contribute to an increased risk of thromboembolism with COVID-19 infection, and differences in the risk of cerebral venous sinus thrombosis appear to exist between the types of vaccines. The benefits of COVID-19 vaccination outweigh any risks. Shared decision-making is necessary when discussing vaccination with patients. Pharmacists play a vital role in dispelling misinformation and disinformation related to the impact of COVID-19 illness and vaccination on reproductive health care.
2019 年冠状病毒病（COVID-19）大流行引发了许多健康问题，包括感染和疫苗对生殖健康的影响。虽然有大量证据表明所有可用的 COVID-19 疫苗是安全的，但与疫苗相关的错误信息和虚假信息仍在传播。作为可及且必不可少的医疗保健工作者，药剂师必须了解与 COVID-19 感染和疫苗接种对生殖保健影响相关的证据。由于 COVID-19 感染、大流行压力和 COVID-19 疫苗接种，已经注意到月经周期发生了变化。COVID-19 感染和疫苗接种并未显示会影响女性生育能力、怀孕率和哺乳。外源性雌激素的使用可能会进一步增加 COVID-19 感染时发生血栓栓塞的风险，并且不同类型的疫苗之间似乎存在脑静脉窦血栓形成风险的差异。接种 COVID-19 疫苗的益处大于任何风险。在与患者讨论疫苗接种时需要共同决策。药剂师在消除与 COVID-19 疾病和疫苗接种对生殖健康影响相关的错误信息和虚假信息方面发挥着至关重要的作用。
