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5680 名因胸部损伤入住英国主要创伤中心的患者的长期生存预测因素。

Predictors of long-term survival in 5,680 patients admitted to a UK major trauma centre with thoracic injuries.

机构信息

University Hospitals Plymouth NHS Trust, UK.

University of Hull, UK.

出版信息

Ann R Coll Surg Engl. 2023 Jul;105(6):540-547. doi: 10.1308/rcsann.2023.0001. Epub 2023 Feb 13.

Abstract

INTRODUCTION

The long-term outcomes of chest trauma are largely unknown. We sought to determine the predictors of in-hospital and long-term survival in patients admitted to a major trauma centre (MTC) with chest injuries and to evaluate spatial patterns of injury in our network area.

METHODS

Retrospective analysis of data collected on the National Trauma Audit Research Network (TARN) database using multivariate analysis and Cox regression analysis. Spatial analysis was performed using ArcGis 10.7.1.

RESULTS

Some 5,680 patients were admitted with chest trauma between December 1999 and December 2019. Median patient age was 45 years and the median Injury Severity Score (ISS) was 20. The proportion of patients who had an operation was 39.8%. Age, blood transfusion, head injury, shock, emergency thoracotomy and heart disease were predictors of hospital mortality ( < 0.05). However, having an operation on concomitant injuries was protective. ISS and Glasgow Coma Score were discriminators of in-hospital mortality (C-indices 0.76 and 0.80, respectively). The 10-year survival values for patients who survived to discharge from hospital and who were aged <40, 50, 60, 70, 80 and >80 years were 99%, 93%, 95%, 87%, 75% and 43%, respectively. Preadmission lung disease and alcohol/drug misuse were poor predictors of long-term survival ( < 0.05). Hotspot analysis revealed the areas with the highest incidents were all close to the MTC.

CONCLUSIONS

The MTC is geographically central to areas with high numbers of trauma incidents. Although emergency thoracotomy was a predictor of poor in-hospital outcomes, having surgery for concomitant injuries improved outcomes. Patients surviving to discharge have good long-term survivals.

摘要

简介

胸部创伤的长期预后在很大程度上尚不清楚。我们旨在确定因胸部损伤入住大型创伤中心(MTC)的患者的院内和长期生存的预测因素,并评估我们网络区域内损伤的空间模式。

方法

使用多变量分析和 Cox 回归分析对国家创伤审核研究网络(TARN)数据库中收集的数据进行回顾性分析。使用 ArcGis 10.7.1 进行空间分析。

结果

1999 年 12 月至 2019 年 12 月期间,共有 5680 名患者因胸部创伤入院。患者的中位年龄为 45 岁,损伤严重程度评分(ISS)的中位数为 20。有 39.8%的患者接受了手术。年龄、输血、头部损伤、休克、急诊开胸术和心脏病是院内死亡的预测因素(<0.05)。然而,对合并伤进行手术是保护因素。ISS 和格拉斯哥昏迷评分是院内死亡的鉴别因素(C 指数分别为 0.76 和 0.80)。存活至出院且年龄<40、50、60、70、80 和>80 岁的患者 10 年生存率分别为 99%、93%、95%、87%、75%和 43%。有预先存在的肺部疾病和滥用酒精/药物是长期生存的不良预测因素(<0.05)。热点分析显示,高发生率的区域都靠近 MTC。

结论

MTC 在地理位置上与创伤事件高发区域接近。尽管急诊开胸术是院内预后不良的预测因素,但对合并伤进行手术可改善预后。存活至出院的患者有较好的长期生存。

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