Department of Poultry Science, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.
Department of Pesticides, Chemistry and Toxicology, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, Egypt.
Biol Trace Elem Res. 2023 Nov;201(11):5379-5388. doi: 10.1007/s12011-023-03592-5. Epub 2023 Feb 15.
Imidacloprid is an insecticide that protects against insects in the agriculture, animal, and poultry production sectors. Since the accumulation of imidacloprid induces adverse impacts on general health status and quality of the food chain, this study tested the impacts on broilers. Besides, selenium nanoparticles were fed to birds to relieve the negative impacts on growth performance and health status. Birds (1-day age, initial weight 46.05 ± 1.0 g) divided into four groups (triplicates) where 15 chicks of each replicate (45 for each group). The first group (control) was fed the basal diet without either selenium or imidacloprid toxicity. The second group was fed selenium nano form at 3 mg/kg. The third group was fed selenium and exposed to imidacloprid at 1/10 LT (3 mg/kg body weight). The fourth group was fed selenium nano form (3 mg/kg) and exposed to imidacloprid at 1/10 LT (3 mg/kg body weight). All groups were kept under the same conditions for 35 days. The final weight and weight gain of birds fed selenium nano form showed marked improvement compared to the imidacloprid-exposed group, while the feed intake and feed conversion ratio markedly reduced. The red blood cells showed higher values in birds fed selenium nano than the control and those exposed to imidacloprid. Interestingly, the hemoglobulin and hematocrit increased in birds fed selenium nano form with or without imidacloprid exposure. Furthermore, the white blood cells increased in birds fed selenium nano form with or without imidacloprid exposure. The total protein, albumin, and globulin were higher in birds fed selenium nanoparticles than those exposed to imidacloprid with or without selenium feeding. Birds in the control and imidacloprid groups had higher aspartate aminotransferase (AST), alanine aminotransferase (ALT), and malondialdehyde levels than the remaining groups. Accordingly, dietary selenium nanoparticles are suggested in broiler feed to cope with the adverse effects of imidacloprid toxicity.
吡虫啉是一种杀虫剂，用于保护农业、动物和家禽生产部门的昆虫。由于吡虫啉的积累会对整体健康状况和食物链质量产生不利影响，因此本研究测试了其对肉鸡的影响。此外，还向鸟类投喂硒纳米颗粒以缓解其对生长性能和健康状况的负面影响。将 1 日龄、初始体重为 46.05±1.0g 的鸡分为 4 组（每组 3 个重复，每个重复 15 只鸡，共 45 只鸡）。第一组（对照组）饲喂基础日粮，不添加硒或吡虫啉毒性。第二组饲喂 3mg/kg 的硒纳米颗粒。第三组饲喂 3mg/kg 硒并暴露于吡虫啉 1/10 LT。第四组饲喂 3mg/kg 的硒纳米颗粒并暴露于吡虫啉 1/10 LT。所有组在相同条件下饲养 35 天。与吡虫啉暴露组相比，饲喂硒纳米颗粒的鸡的最终体重和体重增加明显改善，而采食量和饲料转化率明显降低。与对照组和吡虫啉暴露组相比，饲喂硒纳米颗粒的鸡的红细胞值更高。有趣的是，饲喂硒纳米颗粒的鸡的血红蛋白和红细胞压积在有或没有暴露于吡虫啉的情况下均增加。此外，饲喂硒纳米颗粒的鸡的白细胞数量在有或没有暴露于吡虫啉的情况下增加。与暴露于吡虫啉的鸡相比，饲喂硒纳米颗粒的鸡的总蛋白、白蛋白和球蛋白更高。对照组和吡虫啉组的天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）和丙二醛水平均高于其他组。因此，建议在肉鸡饲料中添加膳食硒纳米颗粒以应对吡虫啉毒性的不利影响。
