Dang Yonglong, Yadav Ram Prakash, Chen Xingqi
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Methods Mol Biol. 2023;2611:285-291. doi: 10.1007/978-1-0716-2899-7_15.
Assay of transposase-accessible chromatin with visualization (ATAC-see), a transposase-mediated imaging technology that enables direct imaging of the accessible genome in situ and deep sequencing to reveal the identity of the imaged elements. Here we image spatial organization of the accessible genome in HT1080 cells with this method.
带可视化的转座酶可及染色质分析（ATAC-see），一种转座酶介导的成像技术，能够对可及基因组进行原位直接成像，并通过深度测序揭示成像元件的身份。在此，我们用这种方法对HT1080细胞中可及基因组的空间组织进行成像。
