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自然语言处理在日本医疗记录中表达疾病特征的一种新应用。

An Alternative Application of Natural Language Processing to Express a Characteristic Feature of Diseases in Japanese Medical Records.

机构信息

Department of Medical Information Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Sojo University, Nishi-ku, Kumamoto, Japan.

出版信息

Methods Inf Med. 2023 Sep;62(3-04):110-118. doi: 10.1055/a-2039-3773. Epub 2023 Feb 21.

Abstract

BACKGROUND

Owing to the linguistic situation, Japanese natural language processing (NLP) requires morphological analyses for word segmentation using dictionary techniques.

OBJECTIVE

We aimed to clarify whether it can be substituted with an open-end discovery-based NLP (OD-NLP), which does not use any dictionary techniques.

METHODS

Clinical texts at the first medical visit were collected for comparison of OD-NLP with word dictionary-based-NLP (WD-NLP). Topics were generated in each document using a topic model, which later corresponded to the respective diseases determined in International Statistical Classification of Diseases and Related Health Problems 10 revision. The prediction accuracy and expressivity of each disease were examined in equivalent number of entities/words after filtration with either term frequency and inverse document frequency (TF-IDF) or dominance value (DMV).

RESULTS

In documents from 10,520 observed patients, 169,913 entities and 44,758 words were segmented using OD-NLP and WD-NLP, simultaneously. Without filtering, accuracy and recall levels were low, and there was no difference in the harmonic mean of the F-measure between NLPs. However, physicians reported OD-NLP contained more meaningful words than WD-NLP. When datasets were created in an equivalent number of entities/words with TF-IDF, F-measure in OD-NLP was higher than WD-NLP at lower thresholds. When the threshold increased, the number of datasets created decreased, resulting in increased values of F-measure, although the differences disappeared. Two datasets near the maximum threshold showing differences in F-measure were examined whether their topics were associated with diseases. The results showed that more diseases were found in OD-NLP at lower thresholds, indicating that the topics described characteristics of diseases. The superiority remained as much as that of TF-IDF when filtration was changed to DMV.

CONCLUSION

The current findings prefer the use of OD-NLP to express characteristics of diseases from Japanese clinical texts and may help in the construction of document summaries and retrieval in clinical settings.

摘要

背景

由于语言环境的原因,日语自然语言处理(NLP)需要使用字典技术进行分词的形态分析。

目的

我们旨在阐明它是否可以被基于开放式探索的 NLP(OD-NLP)所替代,这种 NLP 不使用任何字典技术。

方法

收集首次就诊的临床文本,以比较 OD-NLP 和基于词汇表的 NLP(WD-NLP)。使用主题模型在每个文档中生成主题,该主题后来与国际疾病分类和相关健康问题第 10 修订版中确定的相应疾病相对应。在使用术语频率和逆文档频率(TF-IDF)或优势值(DMV)过滤后,检查每个疾病的预测准确性和表达性,其等价数量的实体/单词。

结果

在观察到的 10520 名患者的文档中,使用 OD-NLP 和 WD-NLP 同时对 169913 个实体和 44758 个单词进行了分割。未经过滤时,准确性和召回率较低,两种 NLP 的调和平均 F 度量之间没有差异。然而,医生报告 OD-NLP 包含的单词比 WD-NLP 更有意义。当使用 TF-IDF 以相等数量的实体/单词创建数据集时,OD-NLP 的 F 度量在较低阈值时高于 WD-NLP。当阈值增加时,创建的数据集数量减少,尽管差异消失,但 F 度量的值增加。在接近最大阈值的两个数据集,其 F 度量存在差异,检查其主题是否与疾病相关。结果表明,在较低的阈值下,OD-NLP 中发现了更多的疾病,表明这些主题描述了疾病的特征。当过滤更改为 DMV 时,这种优势仍然存在。

结论

目前的研究结果倾向于使用 OD-NLP 从日语临床文本中表达疾病的特征,并可能有助于构建文档摘要和检索临床环境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa71/10462427/d226cc31e2c5/10-1055-a-2039-3773-i21010120-1.jpg

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