College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi, Vietnam.
Foreign Animal Disease Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of Korea.
Vet Res Commun. 2023 Sep;47(3):1773-1776. doi: 10.1007/s11259-022-10068-9. Epub 2023 Feb 24.
African swine fever virus (ASFV) causes African swine fever (ASF), a deadly disease affecting both domestic pigs and wild boars. ASF has become endemic in Vietnam since its first appearance in early 2019. Our previous molecular surveillance studies revealed that all the ASFV strains circulating in Vietnam belong to p72 genotype II, p54 genotype II, CD2v serogroup 8, and CVR of B602L gene variant type I. However, the genetic analysis based on the tandem repeat sequences located between I73R and I329L genes revealed three different intergenic region (IGR) variants; I, II, and III. In this study, using ASFV field isolates collected from September 24th to December 27th, 2021, we report, for the first time, novel IGR IV variants circulating in the Vietnamese pig population.
非洲猪瘟病毒（ASFV）引起非洲猪瘟（ASF），这是一种影响家猪和野猪的致命疾病。自 2019 年初首次出现以来，ASF 已在越南流行。我们之前的分子监测研究表明，在越南流行的所有 ASFV 毒株均属于 p72 基因型 II、p54 基因型 II、CD2v 血清群 8 和 B602L 基因变异型 I 的 CVR。然而，基于 I73R 和 I329L 基因之间的串联重复序列的遗传分析显示出三种不同的基因间区（IGR）变体；I、II 和 III。在这项研究中，我们使用 2021 年 9 月 24 日至 12 月 27 日期间从越南猪群中收集的 ASF 田间分离株，首次报告了在越南猪群中循环的新型 IGR IV 变体。
