Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Int J Mol Sci. 2023 Feb 4;24(4):3111. doi: 10.3390/ijms24043111.
In recent years, the phytoconstituents of foods in the Mediterranean diet (MD) have been the subject of several studies for their beneficial effects on human health. The traditional MD is described as a diet heavy in vegetable oils, fruits, nuts, and fish. The most studied element of MD is undoubtedly olive oil due precisely to its beneficial properties that make it an object of interest. Several studies have attributed these protective effects to hydroxytyrosol (HT), the main polyphenol contained in olive oil and leaves. HT has been shown to be able to modulate the oxidative and inflammatory process in numerous chronic disorders, including intestinal and gastrointestinal pathologies. To date, there is no paper that summarizes the role of HT in these disorders. This review provides an overview of the anti-inflammatory and antioxidant proprieties of HT against intestinal and gastrointestinal diseases.
近年来，地中海饮食（MD）中的植物成分因其对人类健康的有益影响而成为多项研究的主题。传统的 MD 被描述为一种富含蔬菜油、水果、坚果和鱼类的饮食。MD 中最受研究的元素无疑是橄榄油，正是因为它的有益特性使其成为关注的对象。多项研究将这些保护作用归因于羟基酪醇（HT），它是橄榄油和叶子中主要的多酚。HT 已被证明能够调节许多慢性疾病中的氧化和炎症过程，包括肠道和胃肠道疾病。迄今为止，还没有一篇论文总结了 HT 在这些疾病中的作用。这篇综述概述了 HT 对肠道和胃肠道疾病的抗炎和抗氧化特性。
