Department of Bio & Medical Big Data (BK4 Program), Division of Life Sciences, Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Republic of Korea.
Department of Pharmaceutical Engineering, Kyungnam University, Changwon, Republic of Korea.
Front Cell Infect Microbiol. 2023 Feb 10;13:1076251. doi: 10.3389/fcimb.2023.1076251. eCollection 2023.
is one of the most notorious genus amongst the family. Monkeypox (MP) is a zoonotic disease that has been spreading throughout Africa. The spread is global, and incidence rates are increasing daily. The spread of the virus is rapid due to human-to-human and animals-to-human transmission. World Health Organization (WHO) has declared monkeypox virus (MPV) as a global health emergency. Since treatment options are limited, it is essential to know the modes of transmission and symptoms to stop disease spread. The information from host-virus interactions revealed significantly expressed genes that are important for the progression of the MP infection. In this review, we highlighted the MP virus structure, transmission modes, and available therapeutic options. Furthermore, this review provides insights for the scientific community to extend their research work in this field.
是正痘病毒科中最臭名昭著的属之一。猴痘（MP）是一种人畜共患病，一直在非洲传播。该疾病的传播是全球性的，发病率每天都在增加。由于人与人之间以及动物与人之间的传播，病毒的传播速度很快。世界卫生组织（WHO）已宣布猴痘病毒（MPV）为全球卫生紧急事件。由于治疗选择有限，了解传播方式和症状以阻止疾病传播至关重要。宿主-病毒相互作用的信息揭示了对 MP 感染进展很重要的显著表达基因。在这篇综述中，我们强调了 MP 病毒结构、传播方式和可用的治疗选择。此外，本综述为科学界提供了在该领域扩展研究工作的思路。
