Çakmaklı Seçil, Özdemir Ayşe, Fırat Hikmet, Aypak Cenk
Department of Family Medicine, University of Health Sciences, Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Department of Pulmonary Diseases, University of Health Sciences, Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
J Taibah Univ Med Sci. 2023 Jan 12;18(4):860-867. doi: 10.1016/j.jtumed.2023.01.001. eCollection 2023 Aug.
Inhaled therapy is the treatment of choice for obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). However, the maximum benefit from such therapy depends on the correct use of inhaler devices. In this study, our primary aim was to evaluate inhaler techniques in patients with asthma and COPD in order to identify common errors. In addition, we investigated the effect of various parameters on the rate of inhaler misuse.
We enrolled a total of 300 asthma/COPD patients, who presented at the Chest Diseases and Family Medicine Outpatient Clinics of a tertiary hospital located in Ankara, Turkey. We used a face-to-face survey that included questions about sociodemographic features and inhaler therapy. Subsequently, we requested patients to demonstrate how they use their inhalers and assessed their inhalation technique according to checklists.
Of the 300 patients, 70.2% used their inhaler drugs incorrectly. The rate of misuse among metered dose inhaler (MDI) users was significantly higher than those using dry powder inhalers (DPIs) (77.6% vs 64%; p = 0.002). When DPI devices were analyzed, the rates of misuse were significantly higher in Handihaler users (p = 0.012) and Diskus inhaler users (p = 0.009) when compared to Sanohaler users. Gender, type of disease (asthma/COPD), duration of inhaler use, and duration of illness had no impact on the rate of misuse. However, an advanced age (>60 years old), a level of education lower than high school, and the use of MDI were all identified as factors associated with misuse. The most common mistake was 'failing to breath out before inhalation' for all types of devices (for MDI: 66.7%, and for DPI: 71.1-82.8%).
The rate of inhaler drug misuse was high. The identification of factors associated with misuse could provide information to implement appropriate actions to reduce the rates of misuse.
吸入疗法是哮喘和慢性阻塞性肺疾病(COPD)等阻塞性肺病的首选治疗方法。然而,这种疗法的最大益处取决于吸入装置的正确使用。在本研究中,我们的主要目的是评估哮喘和COPD患者的吸入技术,以识别常见错误。此外,我们研究了各种参数对吸入器误用率的影响。
我们共招募了300名哮喘/COPD患者,他们在土耳其安卡拉一家三级医院的胸科疾病和家庭医学门诊就诊。我们采用面对面调查,其中包括有关社会人口学特征和吸入疗法的问题。随后,我们要求患者演示他们如何使用吸入器,并根据检查表评估他们的吸入技术。
在300名患者中,70.2%的人吸入药物使用不当。定量吸入器(MDI)使用者的误用率显著高于使用干粉吸入器(DPI)的使用者(77.6%对64%;p = 0.002)。在分析DPI装置时,与使用Sanohaler的使用者相比,Handihaler使用者(p = 0.012)和Diskus吸入器使用者(p = 0.009)的误用率显著更高。性别、疾病类型(哮喘/COPD)、吸入器使用时间和患病时间对误用率没有影响。然而,高龄(>60岁)、高中以下教育水平和使用MDI均被确定为与误用相关的因素。所有类型装置最常见的错误都是“吸气前未呼气”(MDI为66.7%,DPI为71.1 - 82.8%)。
吸入器药物误用率很高。识别与误用相关的因素可为采取适当行动以降低误用率提供信息。