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通过阴极反应形成C(sp)-C(sp)和C(sp)-C(sp)键的最新进展：还原和收敛成对电解

Recent Advances in C(sp)-C(sp) and C(sp)-C(sp) Bond Formation through Cathodic Reactions: Reductive and Convergent Paired Electrolyses.

作者信息

Claraz Aurélie, Masson Géraldine

机构信息

Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Université Paris-Saclay, 1, av. de la Terrasse, Gif-sur-Yvette 91198 Cedex, France.

出版信息

ACS Org Inorg Au. 2021 Dec 22;2(2):126-147. doi: 10.1021/acsorginorgau.1c00037. eCollection 2022 Apr 6.

DOI:10.1021/acsorginorgau.1c00037
PMID:36855458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9954344/
Abstract

The formation of C(sp)-C(sp) and C(sp)-C(sp) bonds is one of the major research goals of synthetic chemists. Electrochemistry is commonly considered to be an appealing means to drive redox reactions in a safe and sustainable fashion and has been utilized for C-C bond-forming reactions. Compared to anodic oxidative methods, which have been extensively explored, cathodic processes are much less investigated, whereas it can pave the way to alternative retrosynthetic disconnections of target molecules and to the discovery of new transformations. This review provides an overview on the recent achievements in the construction of C(sp)-C(sp) and C(sp)-C(sp) bonds via cathodic reactions since 2017. It includes electrochemical reductions and convergent paired electrolyses.

摘要

C(sp)−C(sp)键和C(sp)−C(sp)键的形成是合成化学家的主要研究目标之一。电化学通常被认为是一种以安全、可持续的方式驱动氧化还原反应的有吸引力的手段，并且已被用于C−C键形成反应。与已被广泛探索的阳极氧化方法相比，阴极过程的研究要少得多，然而它可以为目标分子的替代逆合成切断以及新转化反应的发现铺平道路。本文综述了自2017年以来通过阴极反应构建C(sp)−C(sp)键和C(sp)−C(sp)键的最新进展。内容包括电化学还原和收敛成对电解。

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