The First School of Clinical Medicine , Southern Medical University, Guangzhou, 501515, China.
Department of Transfusion Medicine and Department of Laboratory Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, 510282, China.
Clin Exp Med. 2023 Oct;23(6):2813-2827. doi: 10.1007/s10238-023-01028-x. Epub 2023 Mar 1.
Many studies have shown that gut microbiota is closely related to autoimmune diseases (ADs). Studies on gut microbiota and ADs have also increased significantly, but no bibliometric analysis has summarized the association between gut microbiota and ADs. This study aimed to conduct a bibliometric and visual analysis of published studies on gut microbiota and ADs. Based on the Web of Science Core Collection SCI-expanded database, we utilize Excel 2019 and visualization analysis tools VOSviewer and co-occurrence13.2 (COOC13.2) for analysis. A total of 2516 related kinds of literature were included, and the number of papers presented an overall increasing trend. The country/region with the most publications is the USA, the institution is the Harvard Medical School, and the author is Mikael Knip from the USA. Hot research areas include intestinal regulation (such as dysbiosis, short chain fatty acids, and probiotics), multisystem ADs (such as multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease), and immune-related cells (such as T cells, and dendritic cells). Psoriasis, dysbiosis, autoimmune liver disease, and fecal microbiota transplantation may be the future research direction. Our research results can help researchers grasp the current status of ADs and gut microbiota research and find new research directions in the future.
许多研究表明,肠道微生物群与自身免疫性疾病(AD)密切相关。关于肠道微生物群和 AD 的研究也显著增加,但没有文献计量分析总结肠道微生物群与 AD 之间的关联。本研究旨在对肠道微生物群和 AD 的已发表研究进行文献计量和可视化分析。基于 Web of Science 核心合集 SCI-Expanded 数据库,我们使用 Excel 2019 和可视化分析工具 VOSviewer 和 co-occurrence13.2(COOC13.2)进行分析。共纳入 2516 种相关文献,论文数量呈总体上升趋势。发表文献最多的国家/地区是美国,机构是哈佛医学院,作者是来自美国的 Mikael Knip。热门研究领域包括肠道调节(如肠道失调、短链脂肪酸和益生菌)、多系统 AD(如多发性硬化症、类风湿关节炎和炎症性肠病)和免疫相关细胞(如 T 细胞和树突状细胞)。银屑病、肠道失调、自身免疫性肝病和粪便微生物群移植可能是未来的研究方向。我们的研究结果可以帮助研究人员掌握 AD 和肠道微生物群研究的现状,并在未来找到新的研究方向。
Front Cell Infect Microbiol. 2023
Front Cell Infect Microbiol. 2023
Medicine (Baltimore). 2024-1-26
Front Endocrinol (Lausanne). 2022
Medicine (Baltimore). 2023-12-15
Ann Med Surg (Lond). 2025-2-26
Front Microbiol. 2024-12-19
Front Cell Infect Microbiol. 2024
J Alzheimers Dis Rep. 2024-1-29
Front Immunol. 2022
Front Immunol. 2022