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基于中国上海新冠疫情期间方舱医院精神科药物干预的奥密克戎患者心理健康问题危险因素分析

Risk factor analysis of omicron patients with mental health problems in the Fangcang shelter hospital based on psychiatric drug intervention during the COVID-19 pandemic in Shanghai, China.

作者信息

Yu Ping, Bian Xiaolan, Xie Zhihui, Wang Xu, Zhang Xujing, Gu Zhidong, Yang Zhitao, Jing Feng, Qiu Weiyu, Lin Jingsheng, Tang Jie, Huang Chen, Zhang Yibo, Chen Ying, Zhang Zongfeng, Bi Yufang, Shang Hanbing, Chen Erzhen

机构信息

Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Department of Medical Affairs, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Front Psychiatry. 2023 Feb 13;14:1100849. doi: 10.3389/fpsyt.2023.1100849. eCollection 2023.

Abstract

BACKGROUNDS

The widespread coronavirus disease 2019 (COVID-19) outbreak impacted the mental health of infected patients admitted to Fangcang shelter hospital a large-scale, temporary structure converted from existing public venues to isolate patients with mild or moderate symptoms of COVID-19 infection.

OBJECTIVE

This study aimed to investigate the risk factors of the infected patients from a new pharmacological perspective based on psychiatric drug consumption rather than questionnaires for the first time.

METHODS

We summarised the medical information and analysed the prevalence proportion, characteristics, and the related risk factors of omicron variants infected patients in the Fangcang Shelter Hospital of the National Exhibition and Convention Center (Shanghai) from 9 April 2022 to 31 May 2022.

RESULTS

In this study, 6,218 individuals at 3.57% of all admitted patients in the Fangcang shelter were collected suffering from mental health problems in severe conditions including schizophrenia, depression, insomnia, and anxiety who needed psychiatric drug intervention. In the group, 97.44% experienced their first prescription of psychiatric drugs and had no diagnosed historical psychiatric diseases. Further analysis indicated that female sex, no vaccination, older age, longer hospitalization time, and more comorbidities were independent risk factors for the drug-intervened patients.

CONCLUSION

This is the first study to analyse the mental health problems of omicron variants infected patients hospitalised in Fangcang shelter hospitals. The research demonstrated the necessity of potential mental and psychological service development in Fangcang shelters during the COVID-19 pandemic and other public emergency responses.

摘要

背景

2019年冠状病毒病(COVID-19)的广泛爆发对入住方舱医院的感染患者的心理健康产生了大规模影响,方舱医院是由现有公共场所改造而成的大型临时建筑,用于隔离COVID-19感染轻症或中症患者。

目的

本研究旨在首次从新的药理学角度,基于精神科药物消费而非问卷调查,调查感染患者的危险因素。

方法

我们总结了2022年4月9日至2022年5月31日在国家会展中心(上海)方舱医院感染奥密克戎变异株患者的医疗信息,并分析了其患病率、特征及相关危险因素。

结果

本研究共收集了方舱医院6218名患者的信息,占所有入院患者的3.57%,这些患者患有包括精神分裂症、抑郁症、失眠和焦虑症在内的严重心理健康问题,需要精神科药物干预。在该组中,97.44%的患者首次使用精神科药物,且既往无精神疾病诊断史。进一步分析表明,女性、未接种疫苗、年龄较大、住院时间较长以及合并症较多是药物干预患者的独立危险因素。

结论

这是第一项分析方舱医院收治的感染奥密克戎变异株患者心理健康问题的研究。该研究表明,在COVID-19大流行及其他公共应急响应期间,方舱医院开展潜在的心理和精神服务是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cab/9969094/92f44b2ac506/fpsyt-14-1100849-g001.jpg

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