Ruiz de Alegría Puig Carlos, Fernández Martínez Marta, Pablo Marcos Daniel, Agüero Balbín Jesús, Calvo Montes Jorge
Service of Microbiology, University Hospital Marqués de Valdecilla-IDIVAL, Santander, Spain.
Service of Microbiology, University Hospital Marqués de Valdecilla-IDIVAL, Santander, Spain.
Enferm Infecc Microbiol Clin (Engl Ed). 2023 Mar;41(3):169-172. doi: 10.1016/j.eimce.2021.10.012.
Arcobacter butzleri is a gram-negative rod, with microaerobic growth at an optimal temperature of 37°C. It was reported to be the fourth most common Campylobacter-like organism isolated from patients with diarrhoea.
Characterise a potential outbreak of A. butzleri detected in a short period of time in the University Hospital Marqués de Valdecilla.
Eight strains of A. butzleri were detected in our hospital in only two months. Isolates were identified by MALDI-TOF MS system and 16S rDNA sequencing. Enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR) and Pulsed Field Gel Electrophoresis (PFGE) were carried out to assess clonal relationship. Gradient strips (Etest) were used to determine susceptibility by agar diffusion.
ERIC-PCR and PFGE confirmed the lack of clonal relationship between strains. Erythromycin or ciprofloxacin might be appropriate for antibiotic treatment of infections.
A. butzleri is an emerging pathogen with increasing incidence, and may be underestimated.
布氏嗜冷弯曲菌是一种革兰氏阴性杆菌，在37°C的最佳温度下进行微需氧生长。据报道，它是从腹泻患者中分离出的第四种最常见的弯曲菌样生物体。
对在马尔克斯·德·瓦尔迪西利亚大学医院短时间内检测到的布氏嗜冷弯曲菌潜在暴发进行特征描述。
在仅两个月的时间里，我院检测到8株布氏嗜冷弯曲菌。通过基质辅助激光解吸电离飞行时间质谱系统和16S rDNA测序对分离株进行鉴定。进行肠杆菌基因间重复一致序列聚合酶链反应（ERIC-PCR）和脉冲场凝胶电泳（PFGE）以评估克隆关系。使用梯度条（Etest）通过琼脂扩散法确定药敏性。
ERIC-PCR和PFGE证实菌株之间不存在克隆关系。红霉素或环丙沙星可能适用于感染的抗生素治疗。
布氏嗜冷弯曲菌是一种发病率不断上升的新兴病原体，可能被低估了。
