Mary Mawumenyo Mamattah Kirsty, Kusiwaa Adomako Abigail, Nketia Mensah Caleb, Borquaye Lawrence Sheringham
Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Biochem Res Int. 2023 Feb 22;2023:1040478. doi: 10.1155/2023/1040478. eCollection 2023.
Essential oils are known to possess many biological properties such as antimicrobial and antioxidant activities. flowers are used in traditional remedies for diarrhea, cough, fever, and asthma treatment. This work evaluated the chemical composition and the biological activities of essential oils obtained from the flowers and leaves of . The essential oils were extracted using the Clevenger-type apparatus and characterized using GC-MS. In the flower essential oil, a total of 17 compounds were identified, with linalool (23.91%), -terpineol (10.97%), geraniol (10.47%), and phenyl ethyl alcohol (8.65%) being abundant. In the leaf essential oil, a total of 24 compounds were identified, with benzofuran, 2,3-di, hydro-(3.24%), and muurolol (1.40%) being present. Antioxidant activities were assessed using hydrogen peroxide scavenging, phosphomolybdenum, and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging assays. Antimicrobial activities were assessed through a microdilution assay. The essential oil showed antimicrobial activity against test microorganisms with minimum inhibitory concentrations ranging from 25.0 to 50.0 mg/mL. Biofilm inhibition ranged from 27.14 ± 1.0 to 58.99 ± 0.6 mg/mL. The essential oil exhibited total antioxidant capacities which ranged from 17.5 g/g AAE to 83 g/g AAE in the phosphomolybdenum assay. The IC values in the DPPH and hydrogen peroxide radical scavenging assays for both flowers and leaves ranged from 18.66 g/mL to 38.28 g/mL. Both essential oils also displayed good antibiofilm activities, with the concentration required for half-maximal inhibition of biofilm formation being ∼60 mg/mL for both oils. This study shows that essential oils of possess good antioxidant and antimicrobial activities and could be used as a source of natural antioxidants and antimicrobial agents.
已知精油具有许多生物学特性，如抗菌和抗氧化活性。花朵被用于治疗腹泻、咳嗽、发烧和哮喘的传统药物中。这项工作评估了从[植物名称]的花朵和叶子中提取的精油的化学成分和生物学活性。使用克利夫兰型仪器提取精油，并使用气相色谱 - 质谱联用仪进行表征。在花精油中，共鉴定出17种化合物，其中芳樟醇（23.91%）、α-萜品醇（10.97%）、香叶醇（10.47%）和苯乙醇（8.65%）含量丰富。在叶精油中，共鉴定出24种化合物，其中苯并呋喃、2,3 - 二氢 -（3.24%）和桉叶醇（1.40%）存在。通过过氧化氢清除、磷钼酸和2,2 - 二苯基 - 1 - 苦基肼（DPPH）自由基清除试验评估抗氧化活性。通过微量稀释试验评估抗菌活性。该精油对测试微生物显示出抗菌活性，最低抑菌浓度范围为25.0至50.0mg/mL。生物膜抑制范围为27.14±1.0至58.99±0.6mg/mL。在磷钼酸试验中，该精油表现出的总抗氧化能力范围为17.5g/g抗坏血酸当量至83g/g抗坏血酸当量。花朵和叶子在DPPH和过氧化氢自由基清除试验中的IC值范围为18.66g/mL至38.28g/mL。两种精油还都显示出良好的抗生物膜活性，两种精油抑制生物膜形成的半最大抑制浓度所需浓度约为60mg/mL。这项研究表明，[植物名称]的精油具有良好的抗氧化和抗菌活性，可作为天然抗氧化剂和抗菌剂的来源。
