Supernus Pharmaceuticals, Inc., Rockville, MD, USA.
Attention MD, Grand Rapids, MI, USA and Michigan State University College of Human Medicine, East Lansing, MI, USA.
J Atten Disord. 2023 May;27(7):669-697. doi: 10.1177/10870547231158572. Epub 2023 Mar 6.
Among untreated adults, functional impairments associated with ADHD are widespread and cumulative, and can include social, educational, and professional impairments, increased risk of accidents and mortality, and reduced quality of life. Here, we review the most prominent functional impairments in adults with ADHD and summarize evidence describing the potential role of medication in improving outcomes.
Articles related to the search terms "ADHD," "adult," and functional impairments were identified through Google Scholar and PubMed and selected for inclusion based on four criteria: strength of evidence, relevance to current challenges in adult ADHD, impact on the field, and recency of the results.
We identified 179 papers to support the conclusions on the relationship between ADHD and functional impairments, and the impact of pharmacological therapy on functional impairments.
This narrative review provides evidence that pharmacological treatment can be effective in minimizing not only the symptoms of ADHD, but its functional consequences as well.
在未经治疗的成年人中，与 ADHD 相关的功能障碍普遍存在且呈累积性，可能包括社交、教育和职业障碍、事故和死亡率风险增加，以及生活质量降低。在这里，我们综述了 ADHD 成年人中最突出的功能障碍，并总结了描述药物治疗改善结局的潜在作用的证据。
通过 Google Scholar 和 PubMed 检索与搜索词“ADHD”、“成人”和“功能障碍”相关的文章，并根据四项标准选择纳入：证据强度、与成人 ADHD 当前挑战的相关性、对该领域的影响以及结果的时效性。
我们确定了 179 篇论文来支持 ADHD 与功能障碍之间的关系以及药物治疗对功能障碍的影响的结论。
本叙述性综述提供了证据表明，药物治疗不仅可以有效减轻 ADHD 的症状，还可以减轻其功能后果。
