Dhaouadi Sonia, Hechaichi Aicha, Letaief Hajer, Safer Mouna, Mziou Emna, Talmoudi Khouloud, Borgi Chiraz, Chebbi Henda, Somrani Naoufel, Ali Mohamed Belahj, Yahyaoui Souad, Mseddi Amal, Chahed Mohamed Kouni, Ferjani Mustapha, Alaya Nissaf Bouafif-Ben
Observatoire National des Maladies Nouvelles et Emergentes, Tunis, Tunisie.
Faculté de Médecine de Tunis, Université Tunis El Manar, Tunis, Tunisie.
Pan Afr Med J. 2022 Dec 5;43:172. doi: 10.11604/pamj.2022.43.172.35544. eCollection 2022.
the purpose of this study was to describe the clinical and epidemiological features of COVID-19-related deaths in Tunisia notified at the ONMNE (National Observatory of New and emerging Diseases) between 2 March 2020 and 28 February 2021 and to compare COVID-19-related deaths recorded in Tunisia with the international data.
we conducted a national prospective longitudinal descriptive study of data collected from the National Surveillance System of SARS-CoV-2 infection of the ONMNE, Ministry of Health. All COVID-19-related deaths that occurred in Tunisia between March 2020 and February 2021 were included in this study. Data were collected from hospitals, municipalities and regional health departments. Death notifications were collected from multiple data sources (triangulation): The Regional Directorate of Basic Health Care, the ShocRoom (Strategic Health Operations Center), public and private health facilities, the Crisis Unit of the Presidency of the Government, the Directorate for Hygiene and Environmental Protection, the Ministry of Local Affairs and the Environment, as part of the follow-up of confirmed cases by the ONMNE team, positive RT-PCR / TDR post mortem results.
during this study, 8051 deaths were recorded, corresponding to a proportional mortality of 10.4%. The median age was 73 years, with an interquartile range of 17 years. Sex-ratio (M/F) was 1.8. The crude death rate was 69.1/100 000 inhabitants and fatality rate was 3.5%. The analysis of the epidemic curve showed 2 peaks of deaths on 29 October 2020 and 22 January 2021, with 70 and 86 deaths notified respectively. The spatial distribution of mortality showed that the southern Tunisian region had the highest mortality rate. Patients aged 65 and over were most affected (73.7% of cases) with a crude mortality rate of 570.9/100,000 inhabitants and a fatality rate of 13.7%.
prevention strategy based on public health measures must be reinforced by the rapid deployment of anti-COVID-19 vaccination, especially for people at risk of death.
本研究的目的是描述2020年3月2日至2021年2月28日期间在突尼斯国家新兴疾病观察站（ONMNE）通报的与新冠病毒病（COVID-19）相关死亡的临床和流行病学特征，并将突尼斯记录的与COVID-19相关的死亡情况与国际数据进行比较。
我们对从突尼斯卫生部ONMNE的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染国家监测系统收集的数据进行了一项全国前瞻性纵向描述性研究。本研究纳入了2020年3月至2021年2月期间在突尼斯发生的所有与COVID-19相关的死亡病例。数据收集自医院、市政当局和地区卫生部门。死亡报告从多个数据来源收集（三角测量）：基础医疗区域管理局、休克室（战略卫生行动中心）、公共和私人卫生设施、政府总统危机处理小组、卫生与环境保护局、地方事务和环境部，作为ONMNE团队对确诊病例进行随访的一部分，尸检后逆转录聚合酶链反应/转录介导的扩增（RT-PCR/TDR）结果呈阳性。
在本研究期间，记录了8051例死亡病例，相应的比例死亡率为10.4%。年龄中位数为73岁，四分位间距为17岁。性别比（男/女）为1.8。粗死亡率为69.1/10万居民，病死率为3.5%。疫情曲线分析显示，在2020年10月29日和2021年1月22日出现了两个死亡高峰，分别通报了70例和86例死亡病例。死亡率的空间分布显示，突尼斯南部地区的死亡率最高。65岁及以上的患者受影响最大（占病例的73.7%），粗死亡率为570.9/10万居民，病死率为13.7%。
基于公共卫生措施的预防策略必须通过迅速部署抗COVID-19疫苗来加强，特别是针对有死亡风险的人群。
