DeMaria E J, Kenney P R, Merriam M A, Casanova L A, Gann D S
Department of Surgery, Brown University, Providence, Rhode Island.
Ann Surg. 1987 Dec;206(6):738-43. doi: 10.1097/00000658-198712000-00009.
In contrast to other studies, a recent report from the authors' institution has shown a good prognosis for functional recovery in geriatric patients that survive trauma. Because most survivors regained their pre-injury function, the authors examined factors related to nonsurvival in this population of 82 consecutive blunt trauma victims older than the age of 65. Seventeen patients died (21%). Compared with survivors, nonsurvivors were older, had more severe overall injury, and had more severe head and neck trauma but did not differ in severity of trauma that did not involve the head and neck, number of body regions injured, mechanism of injury, or incidence of surgery after injury. Nonsurvivors experienced more frequent complications (82% vs. 33%, p less than 0.05), including a higher incidence of cardiac complications (53% vs. 15%, p less than 0.05) and ventilator dependence for 5 or more days (41% vs. 14%, p less than 0.05). Mortality rates were increased in patients who were 80 years of age or older compared with those ages 65-79 (46% vs. 10%, p less than 0.01), despite injury of similar severity. More frequent complications may contribute to an increased mortality rate in the older group, including an increased incidence of prolonged mechanical ventilation (36% vs. 12%, p less than 0.025), cardiac complications (54% vs. 10%, p less than 0.01), and pneumonia (36% vs. 16%, p less than 0.06). Severely injured patients (Injury Severity Score [ISS] greater than or equal to 25) older than 80 years old had a mortality rate of 80%, and the survivors required permanent nursing home care. Discriminant analysis yielded a reliable method of differentiating survivors from nonsurvivors based on age, ISS, and the presence of cardiac and septic complications. To assess the accuracy of the discriminant function, 61 consecutive patients admitted during 1985 were reviewed prospectively. Discriminant scoring predicted outcome correctly in 92% of these patients. A Geriatric Trauma Survival Score (GTSS) based on the discriminant function was calculated for each of the 143 patients studied and was highly correlated with mortality rate (r = 0.99, p less than 0.001). Thus, the GTSS may serve as a valuable tool for evaluating death in geriatric trauma victims. Furthermore, because complications are potentially avoidable and contribute to increased mortality rates, routine aggressive care for geriatric patients with moderate overall injury is indicated.
与其他研究不同,作者所在机构最近的一份报告显示,老年创伤幸存者的功能恢复预后良好。由于大多数幸存者恢复了受伤前的功能,作者研究了这82名连续的65岁以上钝性创伤受害者中与未存活相关的因素。17名患者死亡(21%)。与幸存者相比,非幸存者年龄更大,总体损伤更严重,头部和颈部创伤更严重,但在非头部和颈部创伤的严重程度、受伤身体部位数量、损伤机制或受伤后手术发生率方面没有差异。非幸存者出现并发症的频率更高(82%对33%,p<0.05),包括心脏并发症发生率更高(53%对15%,p<0.05)以及呼吸机依赖5天或更长时间(41%对14%,p<0.05)。80岁及以上患者的死亡率高于65 - 79岁患者(46%对10%,p<0.01),尽管损伤严重程度相似。老年组并发症更频繁可能导致死亡率增加,包括延长机械通气发生率增加(36%对12%,p<0.025)、心脏并发症(54%对10%,p<0.01)和肺炎(36%对16%,p<0.06)。80岁以上严重受伤患者(损伤严重度评分[ISS]大于或等于25)的死亡率为80%,幸存者需要长期在疗养院护理。判别分析得出了一种基于年龄、ISS以及心脏和感染性并发症的存在来区分幸存者和非幸存者的可靠方法。为评估判别函数的准确性,对1985年收治的61例连续患者进行了前瞻性回顾。判别评分在这些患者中的92%正确预测了结果。为所研究的143例患者中的每一例计算了基于判别函数的老年创伤生存评分(GTSS),其与死亡率高度相关(r = 0.99,p<0.001)。因此,GTSS可作为评估老年创伤受害者死亡情况的有价值工具。此外,由于并发症可能是可避免的且会导致死亡率增加,对于中度总体损伤的老年患者应进行常规积极治疗。