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Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review.

作者信息

Khorasani Amir, Shahbazi-Gahrouei Daryoush, Safari Arash

机构信息

Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.

Department of Radiology, Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC), School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz 71439-14693, Iran.

出版信息

Diagnostics (Basel). 2023 Feb 22;13(5):833. doi: 10.3390/diagnostics13050833.


DOI:10.3390/diagnostics13050833
PMID:36899980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10000685/
Abstract

In recent years, there has been an increasing interest in using nanoparticles in the medical sciences. Today, metal nanoparticles have many applications in medicine for tumor visualization, drug delivery, and early diagnosis, with different modalities such as X-ray imaging, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), etc., and treatment with radiation. This paper reviews recent findings of recent metal nanotheranostics in medical imaging and therapy. The study offers some critical insights into using different types of metal nanoparticles in medicine for cancer detection and treatment purposes. The data of this review study were gathered from multiple scientific citation websites such as Google Scholar, PubMed, Scopus, and Web of Science up through the end of January 2023. In the literature, many metal nanoparticles are used for medical applications. However, due to their high abundance, low price, and high performance for visualization and treatment, nanoparticles such as gold, bismuth, tungsten, tantalum, ytterbium, gadolinium, silver, iron, platinum, and lead have been investigated in this review study. This paper has highlighted the importance of gold, gadolinium, and iron-based metal nanoparticles in different forms for tumor visualization and treatment in medical applications due to their ease of functionalization, low toxicity, and superior biocompatibility.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db61/10000685/e1c193b68541/diagnostics-13-00833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db61/10000685/e1c193b68541/diagnostics-13-00833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db61/10000685/e1c193b68541/diagnostics-13-00833-g001.jpg

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[3]
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[4]
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[5]
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[6]
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[7]
Advancements in tantalum based nanoparticles for integrated imaging and photothermal therapy in cancer management.

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[8]
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[9]
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[10]
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本文引用的文献

[1]
Liposomal Iron Oxide Nanoparticles Loaded with Doxorubicin for Combined Chemo-Photothermal Cancer Therapy.

Pharmaceutics. 2023-1-15

[2]
Radiosensitization with Gadolinium Chelate-Coated Gold Nanoparticles Prevents Aggressiveness and Invasiveness in Glioblastoma.

Int J Nanomedicine. 2023

[3]
Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy.

Nat Commun. 2023-1-18

[4]
Gold nanobipyramid@copper sulfide nanotheranostics for image-guided NIR-II photo/chemodynamic cancer therapy with enhanced immune response.

Acta Biomater. 2023-3-1

[5]
Cascade two-stage tumor re-oxygenation and immune re-sensitization mediated by self-assembled albumin-sorafenib nanoparticles for enhanced photodynamic immunotherapy.

Acta Pharm Sin B. 2022-11

[6]
Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine.

Int J Mol Sci. 2022-11-2

[7]
Metabolic reprogramming mediated PD-L1 depression and hypoxia reversion to reactivate tumor therapy.

J Control Release. 2022-12

[8]
Novel MR imaging nanoprobe for hepatocellular carcinoma detection based on manganese-zinc ferrite nanoparticles: in vitro and in vivo assessments.

J Cancer Res Clin Oncol. 2023-7

[9]
Clinical translational barriers against nanoparticle-based imaging agents.

Adv Drug Deliv Rev. 2022-12

[10]
Nanoparticle Diagnostics and Theranostics in the Clinic.

J Nucl Med. 2022-12

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