如何应对噬菌体：具有机制见解的方法综述。
How to Tackle Bacteriophages: The Review of Approaches with Mechanistic Insight.
机构信息
Department of Bacterial Molecular Genetics, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdansk, Poland.
Institut de Physique et Chimie des Matériaux de Strasbourg, Université de Strasbourg, CNRS, UMR7504, 23 rue du Loess, CEDEX 2, F-67034 Strasbourg, France.
出版信息
Int J Mol Sci. 2023 Feb 23;24(5):4447. doi: 10.3390/ijms24054447.
Bacteriophage-based applications have a renaissance today, increasingly marking their use in industry, medicine, food processing, biotechnology, and more. However, phages are considered resistant to various harsh environmental conditions; besides, they are characterized by high intra-group variability. Phage-related contaminations may therefore pose new challenges in the future due to the wider use of phages in industry and health care. Therefore, in this review, we summarize the current knowledge of bacteriophage disinfection methods, as well as highlight new technologies and approaches. We discuss the need for systematic solutions to improve bacteriophage control, taking into account their structural and environmental diversity.
基于噬菌体的应用在今天迎来了复兴，越来越多地在工业、医学、食品加工、生物技术等领域得到应用。然而，噬菌体被认为能抵抗各种恶劣的环境条件；此外，它们的特点是组内变异性高。因此，由于噬菌体在工业和医疗保健领域的广泛应用，噬菌体相关污染可能会在未来带来新的挑战。因此，在这篇综述中，我们总结了目前噬菌体消毒方法的知识，并强调了新技术和方法。我们讨论了需要系统的解决方案来改善噬菌体的控制，同时考虑到它们的结构和环境多样性。
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