Amirzade-Iranaq Mohammad Taher, Omidi Mahdi, Bakhsheshi-Rad Hamid Reza, Saberi Abbas, Abazari Somayeh, Teymouri Nadia, Naeimi Farid, Sergi Claudia, Ismail Ahmad Fauzi, Sharif Safian, Berto Filippo
Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Department of Materials and Metallurgical Engineering, Amirkabir University of Technology, Tehran, Iran.
Materials (Basel). 2023 Feb 25;16(5):1919. doi: 10.3390/ma16051919.
This study attempts to synthesize MgZn/TiO-MWCNTs composites with varying TiO-MWCNT concentrations using mechanical alloying and a semi-powder metallurgy process coupled with spark plasma sintering. It also aims to investigate the mechanical, corrosion, and antibacterial properties of these composites. When compared to the MgZn composite, the microhardness and compressive strength of the MgZn/TiO-MWCNTs composites were enhanced to 79 HV and 269 MPa, respectively. The results of cell culture and viability experiments revealed that incorporating TiO-MWCNTs increased osteoblast proliferation and attachment and enhanced the biocompatibility of the TiO-MWCNTs nanocomposite. It was observed that the corrosion resistance of the Mg-based composite was improved and the corrosion rate was reduced to about 2.1 mm/y with the addition of 10 wt% TiO-1 wt% MWCNTs. In vitro testing for up to 14 days revealed a reduced degradation rate following the incorporation of TiO-MWCNTs reinforcement into a MgZn matrix alloy. Antibacterial evaluations revealed that the composite had antibacterial activity, with an inhibition zone of 3.7 mm against . The MgZn/TiO-MWCNTs composite structure has great potential for use in orthopedic fracture fixation devices.
本研究试图通过机械合金化以及结合放电等离子烧结的半粉末冶金工艺，合成具有不同TiO - MWCNT浓度的MgZn/TiO - MWCNTs复合材料。它还旨在研究这些复合材料的力学、腐蚀和抗菌性能。与MgZn复合材料相比，MgZn/TiO - MWCNTs复合材料的显微硬度和抗压强度分别提高到了79 HV和269 MPa。细胞培养和活力实验结果表明，加入TiO - MWCNTs可促进成骨细胞增殖和附着，并增强了TiO - MWCNTs纳米复合材料的生物相容性。观察到，添加10 wt% TiO - 1 wt% MWCNTs后，镁基复合材料的耐腐蚀性得到改善，腐蚀速率降低至约2.1 mm/y。长达14天的体外测试表明，在MgZn基体合金中加入TiO - MWCNTs增强相后，降解速率降低。抗菌评估显示，该复合材料具有抗菌活性，对……的抑菌圈为3.7 mm。MgZn/TiO - MWCNTs复合结构在骨科骨折固定装置中具有巨大的应用潜力。
