Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates.
作者信息
Uffelmann Emil, Posthuma Danielle, Peyrot Wouter J
机构信息
Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands.
Department of Child and Adolescent Psychiatry and Pediatric Psychology, Section Complex Trait Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam University Medical Center, Amsterdam, The Netherlands.
出版信息
Sci Rep. 2023 Mar 14;13(1):4219. doi: 10.1038/s41598-023-29428-9.
Abstract
摘要
Zotero 插件