Polish National Cancer Registry, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Epidemiology Department, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
J Cancer Surviv. 2023 Jun;17(3):657-662. doi: 10.1007/s11764-023-01358-5. Epub 2023 Mar 17.
We aimed to identify granular groups with an increased risk of suicide among adolescents and young adult (AYA) patients with a previous malignant neoplasm diagnosis.
We deployed a cohort of all cases of primary malignant neoplasms diagnosed between the 1st of January 2009 and the 31st of December 2019 among individuals aged 15-39 years registered in the Polish National Cancer Registry. To assess the risk of suicide in comparison with the general AYA population, we calculated sex-age-year standardized mortality ratios (SMR) with 95% confidence intervals (CI).
A total of 50,298 cancer patients (22,111 men and 28,187 women) were included in this study. The risk of suicide for AYA after cancer diagnosis was 2.39-fold higher than that for AYA in the general population (SMR 2.39, 95% CI 1.69 to 3.28). The risk in women (SMR 4.18, 95% CI 1.68 to 8.62) was higher than that in men (SMR 2.18, 95% CI 1.48 to 3.09). A significantly higher risk of suicide was observed in men with testicular cancer (SMR 2.46, 95% CI 1.37 to 4.05).
Polish AYA diagnosed with cancer had an almost 2.5-fold higher risk of suicide than the general AYA population. The particular risk group was men with testicular cancer within 2-3 and 5-10 years after cancer diagnosis.
To better identify patients at risk of suicide, there is a need to create or adapt screening tools, educate cancer care providers and family physicians, and integrate psychological services into select cancer care specialties.
我们旨在确定患有既往恶性肿瘤诊断的青少年和年轻成人（AYA）患者中自杀风险增加的颗粒组。
我们部署了一个队列，该队列包括 2009 年 1 月 1 日至 2019 年 12 月 31 日期间在波兰国家癌症登记处注册的年龄在 15-39 岁之间的个体中诊断出的原发性恶性肿瘤的所有病例。为了与一般 AYA 人群相比评估自杀风险，我们计算了性别-年龄-年份标准化死亡率比（SMR）及其 95％置信区间（CI）。
本研究共纳入 50298 例癌症患者（22111 名男性和 28187 名女性）。与一般 AYA 人群相比，癌症诊断后 AYA 的自杀风险高 2.39 倍（SMR 2.39，95％CI 1.69 至 3.28）。女性（SMR 4.18，95％CI 1.68 至 8.62）的风险高于男性（SMR 2.18，95％CI 1.48 至 3.09）。睾丸癌患者的自杀风险明显更高（SMR 2.46，95％CI 1.37 至 4.05）。
波兰被诊断患有癌症的 AYA 自杀风险比一般 AYA 人群高近 2.5 倍。特定的风险群体是癌症诊断后 2-3 年和 5-10 年内患有睾丸癌的男性。
为了更好地识别有自杀风险的患者，需要创建或改编筛查工具，教育癌症护理提供者和家庭医生，并将心理服务整合到某些癌症护理专业中。
