Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nat Rev Immunol. 2023 May;23(5):267-268. doi: 10.1038/s41577-023-00868-8.
H5N1 avian influenza viruses of the A/goose/Guangdong/1/96 lineage have been circulating in wild birds for many years, have inflicted significant economic losses on the poultry industry and have caused zoonotic infections since 1997. However, the recent spread of avian H5N1 virus to the Americas and its detection in mammals have raised concerns about its pandemic potential.
H5N1 禽流感病毒属于 A/鹅/广东/1/96 谱系,多年来一直在野生鸟类中传播,自 1997 年以来给家禽业造成了重大经济损失,并导致了人畜共患感染。然而,最近禽流感 H5N1 病毒传播到美洲以及在哺乳动物中检测到该病毒,引起了人们对其大流行潜力的担忧。