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埃塞俄比亚遭受压力的成年人中的创伤后应激障碍及相关因素:一项荟萃分析与系统评价

Post-traumatic stress disorder and associated factors among adults exposed to stress in Ethiopia: A meta-analysis and systematic review.

作者信息

Melkam Mamaru, Tinsae Techilo, Andualem Fantahun, Nakie Girum

机构信息

Department of Psychiatry, University of Gondar College of Medicine and Health Sciences, Gondar, Ethiopia.

出版信息

SAGE Open Med. 2023 Mar 17;11:20503121231160884. doi: 10.1177/20503121231160884. eCollection 2023.

Abstract

OBJECTIVE

Post-traumatic stress disorder is a complex psychiatric disorder that develops after exposure to traumatic events, such as violent physical assaults, accidents, rape, natural disasters, and conflicts, stranger than usual human experiences. The typical presentation of intrusive thoughts, the persistence of the trauma, the avoidance of pertinent stimuli, emotional numbness, and physiological hyperarousal are the characteristics of this anxiety symptom. Despite the presence of a study conducted on this problem, the pooled effect, particularly in Ethiopia, is not known; therefore, this study assessed the allover burden of post-traumatic stress disorder.

METHOD

The available study was extracted and conducted on post-traumatic stress disorder and its associated factors in Ethiopia by three independent authors. The data were analyzed by using STATA version 11 after extraction was done on a Microsoft Excel spreadsheet. The random-effect model was used to estimate the pooled effect size of post-traumatic stress disorder and its effect in the previous studies with 95% confidence intervals. Funnel plots analysis and Egger regression tests were conducted to detect the presence of publication bias. A subgroup analysis and a sensitivity analysis were done.

RESULT

Thirteen (13) studies were included with a total of 5874 study participants in this meta-analysis and systematic reviews. The pooled prevalence of post-traumatic stress disorder in Ethiopia was 39.28% with a 95% confidence interval (26.54, 52.01). Poor social support (adjusted odds ratio = 2.86; 95% confidence interval (1.81, 4.53)), being female (adjusted odds ratio = 1.89; 95% confidence interval (1.53, 2.34)), presence of previous mental illness (adjusted odds ratio = 4.72; 95% confidence interval (2.62, 8.36)), and witness (adjusted odds ratio = 2.01; 95% confidence interval (1.30, 3.11)) were associated with post-traumatic stress disorder.

CONCLUSION

The burden of post-traumatic stress disorder in this meta-analysis and systematic review is high; therefore, immediate intervention is needed for those specific traumatized individuals.

摘要

目的

创伤后应激障碍是一种复杂的精神障碍,在经历创伤性事件后出现,如暴力人身攻击、事故、强奸、自然灾害和冲突等超乎寻常的人类经历。侵入性思维、创伤的持续存在、对相关刺激的回避、情感麻木和生理过度觉醒是这种焦虑症状的典型表现。尽管针对这个问题已有研究,但综合效应,尤其是在埃塞俄比亚的情况尚不清楚;因此,本研究评估了创伤后应激障碍的总体负担。

方法

由三位独立作者提取并开展了关于埃塞俄比亚创伤后应激障碍及其相关因素的现有研究。在Microsoft Excel电子表格上完成数据提取后,使用STATA 11版本进行数据分析。采用随机效应模型来估计创伤后应激障碍的综合效应大小及其在先前研究中的效应,并给出95%置信区间。进行漏斗图分析和Egger回归检验以检测发表偏倚的存在。进行了亚组分析和敏感性分析。

结果

本荟萃分析和系统评价纳入了13项研究,共有5874名研究参与者。埃塞俄比亚创伤后应激障碍的综合患病率为39.28%,95%置信区间为(26.54, 52.01)。社会支持差(调整优势比 = 2.86;95%置信区间(1.81, 4.53))、女性(调整优势比 = 1.89;95%置信区间(1.53, 2.34))、既往有精神疾病(调整优势比 = 4.72;95%置信区间(2.62, 8.36))以及目睹创伤事件(调整优势比 = 2.01;95%置信区间(1.30, 3.11))与创伤后应激障碍相关。

结论

本荟萃分析和系统评价中创伤后应激障碍的负担很高;因此,需要对那些特定的受创伤个体立即进行干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8090/10026129/6efcd8d735a2/10.1177_20503121231160884-fig1.jpg

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