Research Center for Evidence-Based Medicine, A JBI Centre of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
Faculty of Veterinary Medicine, Department of Clinical Sciences, University of Tabriz, Tabriz, Iran.
Vet Med Sci. 2023 May;9(3):1395-1406. doi: 10.1002/vms3.1127. Epub 2023 Mar 23.
Actions that are taken to preserve effective antibacterial agents and eliminate transmission of resistant organisms are crucial to prevent a catastrophic postantibiotic era. In this systematic review, we searched and appraised relevant texts and expert opinions to determine effective strategies to tackle bacterial resistance worldwide. We considered expert opinions, consensus, current discourses, comments, assumptions or assertions and discussion papers published in English. We searched following databases for expert opinion-based literature: MEDLINE, CINAHL, ISI Web of Knowledge, SCOPUS, Cochrane Central Register of Controlled Trials and World Health Organization (WHO). We extracted the textual data from texts using a standardised data extraction tool. Textual pooling was not possible, so the conclusions were presented in a narrative form. Eighteen texts were included in this review. The findings show that, the most repeated policies and strategies include implementing and strengthening bacterial resistance surveillance, developing national guidelines, improving public awareness; enhancing home and everyday life hygiene; improving prescribing patterns, improving laboratories capacity, promoting innovation and research in new drugs and technology and strengthening coordination. This review systematically gathered strategies that were recommended by textual publications. To our knowledge, this was the first systematic review of text and opinion in the field of bacterial resistance. These results can be used by policymakers, hospital managers, and governments, alongside the results of quantitative and qualitative systematic reviews.
采取行动保护有效的抗菌药物并消除耐药菌的传播，对于防止出现后抗生素时代的灾难性局面至关重要。在本次系统评价中，我们搜索并评估了相关文献和专家意见，以确定全球范围内应对细菌耐药性的有效策略。我们考虑了专家意见、共识、当前的讨论、评论、假设或断言以及在英文期刊上发表的讨论文件。我们在以下数据库中搜索了基于专家意见的文献：MEDLINE、CINAHL、ISI Web of Knowledge、SCOPUS、Cochrane 对照试验中心注册库和世界卫生组织（WHO）。我们使用标准化的数据提取工具从文本中提取文本数据。由于无法进行文本合并，因此以叙述形式呈现结论。本综述纳入了 18 篇文献。研究结果表明，最常被提及的政策和策略包括实施和加强细菌耐药性监测、制定国家指南、提高公众意识、加强家庭和日常生活卫生、改善处方模式、提高实验室能力、促进新药和技术的创新和研究以及加强协调。本综述系统地收集了文献中推荐的策略。据我们所知，这是细菌耐药性领域文本和意见的首次系统评价。这些结果可与定量和定性系统评价的结果一起供政策制定者、医院管理者和政府使用。
