中国重庆30-79岁汉族居民中有害饮酒与饮茶对高尿酸血症的相互作用

Interaction of Harmful Alcohol Use and Tea Consumption on Hyperuricemia Among Han Residents Aged 30-79 in Chongqing, China.

作者信息

Ding Xianbin, Chen Liling, Tang Wenge, Chen Ting, Xu Jingru, Yang Xianxian, Ding Rui, Tang Xiaojun

机构信息

Chongqing Municipal Center for Disease Control and Prevention, Chongqing, People's Republic of China.

First Medical College, Chongqing Medical University, Chongqing, People's Republic of China.

出版信息

Int J Gen Med. 2023 Mar 17;16:973-981. doi: 10.2147/IJGM.S401889. eCollection 2023.

DOI:10.2147/IJGM.S401889

PMID:36959974

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10029929/

Abstract

OBJECTIVE

The prevalence of hyperuricemia appears to be high worldwide. We aimed to explore the interaction between harmful alcohol use and tea consumption on hyperuricemia.

METHODS

This study recruited 22,449 Han residents based on the data from the China Multi-Ethnic Cohort (CMEC) study, Chongqing province, to have a face-to-face electronic questionnaire, physical examination, and clinical laboratory tests. The difference in hyperuricemia between the different populations was compared by the Chi-square test. The interaction between harmful alcohol use and tea consumption was analyzed by the multivariate logistic regression model.

RESULTS

Amongst 22,449 participants, the mean age was 51.5±11.8 years, and 46.83% of them were males. The proportion of harmful alcohol use, tea consumption, and harmful alcohol use and tea consumption were 14.01%, 21.01%, and 6.54%, respectively. Multivariate logistic regression showed that the odds ratio (OR) of harmful alcohol use and tea consumption (OR=2.21, 95% CI: 1.58-3.10) was greater than that of harmful alcohol use (OR=1.63, 95% CI:1.17-2.27) and tea consumption (OR=1.34, 95% CI:1.10-1.63). Among males, the results were similar (harmful alcohol use and tea consumption: OR=2.02, 95% CI: 1.43-2.84; harmful alcohol use: OR=1.61, 95% CI: 1.14-2.27; tea consumption: OR=1.28, 95% CI: 1.05-1.57). However, among females, the odds ratio of harmful alcohol use and tea consumption (OR=15.50, 95% CI: 1.36-176.50) was more than 10 times than that of only harmful alcohol use (OR=1.55, 95% CI: 0.42-5.69) or tea consumption (OR=1.22, 95% CI: 0.52-2.82).

CONCLUSION

The interaction of harmful alcohol use and tea consumption was a positive risk for hyperuricemia in Han residents aged 30-79 years in China.

摘要

目的

高尿酸血症在全球范围内的患病率似乎较高。我们旨在探讨有害饮酒与饮茶对高尿酸血症的相互作用。

方法

本研究基于中国多民族队列（CMEC）研究重庆地区的数据，招募了22449名汉族居民，进行面对面电子问卷调查、体格检查和临床实验室检测。采用卡方检验比较不同人群高尿酸血症的差异。通过多因素logistic回归模型分析有害饮酒与饮茶之间的相互作用。

结果

在22449名参与者中，平均年龄为51.5±11.8岁，其中46.83%为男性。有害饮酒、饮茶以及有害饮酒且饮茶的比例分别为14.01%、21.01%和6.54%。多因素logistic回归显示，有害饮酒且饮茶的比值比（OR）（OR=2.21，95%CI：1.58 - 3.10）大于有害饮酒（OR=1.63，95%CI：1.17 - 2.27）和饮茶（OR=1.34，95%CI：1.10 - 1.63）。在男性中，结果相似（有害饮酒且饮茶：OR=2.02，95%CI：1.43 - 2.84；有害饮酒：OR=1.61，95%CI：1.14 - 2.27；饮茶：OR=1.28，95%CI：1.05 - 1.57）。然而，在女性中，有害饮酒且饮茶的比值比（OR=15.50，95%CI：1.36 - 176.50）比仅有害饮酒（OR=1.55，95%CI：0.42 - 5.69）或饮茶（OR=1.22，95%CI：0.52 - 2.82）高出10倍以上。