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用于睡眠纺锤波检测的分层融合检测算法

Hierarchical fusion detection algorithm for sleep spindle detection.

作者信息

Chen Chao, Meng Jiayuan, Belkacem Abdelkader Nasreddine, Lu Lin, Liu Fengyue, Yi Weibo, Li Penghai, Liang Jun, Huang Zhaoyang, Ming Dong

机构信息

Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.

Key Laboratory of Complex System Control Theory and Application, Tianjin University of Technology, Tianjin, China.

出版信息

Front Neurosci. 2023 Mar 9;17:1105696. doi: 10.3389/fnins.2023.1105696. eCollection 2023.

Abstract

BACKGROUND

Sleep spindles are a vital sign implying that human beings have entered the second stage of sleep. In addition, they can effectively reflect a person's learning and memory ability, and clinical research has shown that their quantity and density are crucial markers of brain function. The "gold standard" of spindle detection is based on expert experience; however, the detection cost is high, and the detection time is long. Additionally, the accuracy of detection is influenced by subjectivity.

METHODS

To improve detection accuracy and speed, reduce the cost, and improve efficiency, this paper proposes a layered spindle detection algorithm. The first layer used the Morlet wavelet and RMS method to detect spindles, and the second layer employed an improved k-means algorithm to improve spindle detection efficiency. The fusion algorithm was compared with other spindle detection algorithms to prove its effectiveness.

RESULTS

The hierarchical fusion spindle detection algorithm showed good performance stability, and the fluctuation range of detection accuracy was minimal. The average value of precision was 91.6%, at least five percentage points higher than other methods. The average value of recall could reach 89.1%, and the average value of specificity was close to 95%. The mean values of accuracy and F1-score in the subject sample data were 90.4 and 90.3%, respectively. Compared with other methods, the method proposed in this paper achieved significant improvement in terms of precision, recall, specificity, accuracy, and F1-score.

CONCLUSION

A spindle detection method with high steady-state accuracy and fast detection speed is proposed, which combines the Morlet wavelet with window RMS and an improved k-means algorithm. This method provides a powerful tool for the automatic detection of spindles and improves the efficiency of spindle detection. Through simulation experiments, the sampled data were analyzed and verified to prove the feasibility and effectiveness of this method.

摘要

背景

睡眠纺锤波是人类进入睡眠第二阶段的一个重要标志。此外,它们能有效反映一个人的学习和记忆能力,临床研究表明其数量和密度是脑功能的关键指标。纺锤波检测的“金标准”基于专家经验;然而,检测成本高且检测时间长。此外,检测准确性受主观性影响。

方法

为提高检测准确性和速度、降低成本并提高效率,本文提出一种分层纺锤波检测算法。第一层使用Morlet小波和均方根(RMS)方法检测纺锤波,第二层采用改进的k均值算法提高纺锤波检测效率。将该融合算法与其他纺锤波检测算法进行比较以证明其有效性。

结果

分层融合纺锤波检测算法表现出良好的性能稳定性,检测准确性的波动范围最小。精确率平均值为91.6%,比其他方法至少高五个百分点。召回率平均值可达89.1%,特异性平均值接近95%。受试者样本数据中的准确率和F1分数平均值分别为90.4%和90.3%。与其他方法相比,本文提出的方法在精确率、召回率、特异性、准确率和F1分数方面均有显著提高。

结论

提出一种结合Morlet小波、窗口均方根和改进k均值算法的具有高稳态准确性和快速检测速度的纺锤波检测方法。该方法为纺锤波的自动检测提供了有力工具,提高了纺锤波检测效率。通过仿真实验对采样数据进行分析和验证,证明了该方法的可行性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4c2/10035334/f490de9ed94c/fnins-17-1105696-g001.jpg

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