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中国上海皮肤病患者的变应原致敏情况。

Allergen Sensitization in Patients with Skin Diseases in Shanghai, China.

作者信息

Zheng Chunjiao, Zou Ying

机构信息

Skin and Cosmetic Research Department, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

出版信息

J Asthma Allergy. 2023 Mar 20;16:305-313. doi: 10.2147/JAA.S402165. eCollection 2023.

DOI:10.2147/JAA.S402165
PMID:36970654
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10038006/
Abstract

INTRODUCTION

Allergen distribution has obvious geographical characteristics. Understanding local epidemiological data may provide evidence-based strategies for the prevention and management of disease. We investigated the distribution of allergen sensitization in patients with skin diseases in Shanghai, China.

METHODS

Data from tests for serum-specific immunoglobulin E were collected from 714 patients with three skin diseases who visited the Shanghai Skin Disease Hospital from January 2020 to February 2022. The prevalence of 16 allergen species, as well as age, sex, and disease-group differences in allergen sensitization, were investigated.

RESULTS

and were the most common aeroallergen species to cause allergic sensitization in patients with skin diseases, whereas shrimp and crab were the most common food-allergen species. Children were more susceptible to various allergen species. With regard to sex differences, males were sensitized to more allergen species than females. Patients suffering from atopic dermatitis were sensitized to more allergenic species than patients with non-atopic eczema or urticaria.

CONCLUSION

Allergen sensitization in patients with skin diseases in Shanghai differed by age, sex, and disease type. Knowing the prevalence of allergen sensitization across age, sex, and disease type may help facilitate diagnostic and intervention efforts, and guide the treatment and management of skin diseases in Shanghai.

摘要

引言

变应原分布具有明显的地理特征。了解当地流行病学数据可为疾病的预防和管理提供循证策略。我们调查了中国上海皮肤病患者的变应原致敏情况。

方法

收集了2020年1月至2022年2月期间前往上海市皮肤病医院就诊的714例三种皮肤病患者的血清特异性免疫球蛋白E检测数据。调查了16种变应原的患病率,以及变应原致敏在年龄、性别和疾病组方面的差异。

结果

[此处原文缺失具体内容]是皮肤病患者中引起过敏致敏最常见的气传变应原种类,而虾和蟹是最常见的食物变应原种类。儿童更容易对各种变应原种类致敏。在性别差异方面,男性比女性对更多的变应原种类致敏。患有特应性皮炎的患者比非特应性湿疹或荨麻疹患者对更多的变应原种类致敏。

结论

上海皮肤病患者的变应原致敏情况在年龄、性别和疾病类型上存在差异。了解不同年龄、性别和疾病类型的变应原致敏患病率可能有助于促进诊断和干预工作,并指导上海皮肤病的治疗和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16f/10038006/4e6ab0b36dfe/JAA-16-305-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16f/10038006/4e6ab0b36dfe/JAA-16-305-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16f/10038006/4e6ab0b36dfe/JAA-16-305-g0001.jpg

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