Oncham Supa, Udomsubpayakul Umaporn, Laisuan Wannada
Division of Allergy Immunology and Rheumatology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Asia Pac Allergy. 2018 Apr 24;8(2):e17. doi: 10.5415/apallergy.2018.8.e17. eCollection 2018 Apr.
The global prevalence of allergic rhinitis, asthma, and atopic dermatitis has risen significantly over the last 2 decades. Allergic sensitization to aeroallergen is a major risk factor in developing the allergic disease. The prevalence of aeroallergen sensitization varies in different regions and countries.
To determine the prevalence of common aeroallergen sensitization and the atopic status among adult patients.
A cross-sectional, retrospective study. The data were collected from medical records and database of the result of skin prick test of patients who had the allergic symptoms or chronic urticaria in adult allergy clinic, Ramathibodi hospital from January 2004 to December 2015.
A total of 1,516 of patients (female, 1,118 [73.7%]) were enrolled. The mean ages of participants were 41.34 (standard deviation, ±16.5) years. Fifty-eight percent (58%) of patients were diagnosed with allergic rhinitis, 19.7%, 3.2%, and 9.2% with asthma, atopic dermatitis, and chronic urticaria respectively. In the chronic urticaria group, 57.4% underwent the positive skin prick test to common aeroallergens. Mites were responsible for the most common inhaled allergen sensitization in this study as 50.1% of , 32% of , and 31.5% of house dust. Cockroach was the second most common aeroallergen sensitization as 32.3% followed by grass pollen, Bermuda (21.1%) and timothy (13.6%). The animal dander, cat and dog, occupied 12.9 and 10% respectively.
Mites were the most common cause of aeroallergen sensitization in all patients followed by cockroach, grass pollen, and animal dander. However, Bermuda sensitization has increased significantly in the last 6 years.
在过去20年中，全球过敏性鼻炎、哮喘和特应性皮炎的患病率显著上升。对气传变应原的过敏致敏是发生过敏性疾病的主要危险因素。气传变应原致敏的患病率在不同地区和国家有所不同。
确定成年患者中常见气传变应原致敏的患病率和特应状态。
一项横断面回顾性研究。数据收集自2004年1月至2015年12月在拉玛蒂博迪医院成人过敏门诊有过敏症状或慢性荨麻疹患者的病历和皮肤点刺试验结果数据库。
共纳入1516例患者（女性1118例[73.7%]）。参与者的平均年龄为41.34岁（标准差±16.5）。58%的患者被诊断为过敏性鼻炎，19.7%、3.2%和9.2%的患者分别被诊断为哮喘、特应性皮炎和慢性荨麻疹。在慢性荨麻疹组中，57.4%的患者对常见气传变应原皮肤点刺试验呈阳性。在本研究中，螨虫是最常见的吸入性变应原致敏原因，占屋尘的50.1%、粉尘螨的32%和屋尘螨的31.5%。蟑螂是第二常见的气传变应原致敏原因，为32.3%，其次是百慕大草花粉（21.1%）和梯牧草花粉（13.6%）。动物皮屑，猫和狗，分别占12.9%和10%。
在所有患者中，螨虫是气传变应原致敏的最常见原因，其次是蟑螂、草花粉和动物皮屑。然而，在过去6年中，百慕大草花粉致敏显著增加。
