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中国四环素类抗生素的来源与分布:综述

The Source and Distribution of Tetracycline Antibiotics in China: A Review.

作者信息

Chang Donghao, Mao Yizhi, Qiu Wei, Wu Yunshu, Cai Baiyan

机构信息

Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education & Heilongjiang Provincial Key Laboratory of Ecological Restoration and Resource Utilization for Cold Region & Key Laboratory of Molecular Biology, College of Heilongjiang Province & School of Life Sciences, Heilongjiang University, Harbin 150080, China.

出版信息

Toxics. 2023 Feb 24;11(3):214. doi: 10.3390/toxics11030214.

DOI:10.3390/toxics11030214
PMID:36976979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10052762/
Abstract

In recent years, antibiotics have been listed as a new class of environmental pollutants. Tetracycline antibiotics (TCs) used in human medical treatment, animal husbandry and agricultural production are the most widely used antibiotics. Due to their wide range of activities and low cost, their annual consumption is increasing. TCs cannot be completely metabolized by humans and animals. They can be abused or overused, causing the continuous accumulation of TCs in the ecological environment and potential negative effects on non-target organisms. These TCs may spread into the food chain and pose a serious threat to human health and the ecology. Based on the Chinese environment, the residues of TCs in feces, sewage, sludge, soil and water were comprehensively summarized, as well as the potential transmission capacity of air. This paper collected the concentrations of TCs in different media in the Chinese environment, contributing to the collection of a TC pollutant database in China, and facilitating the monitoring and treatment of pollutants in the future.

摘要

近年来,抗生素已被列为一类新的环境污染物。用于人类医疗、畜牧业和农业生产的四环素类抗生素(TCs)是使用最广泛的抗生素。由于其活性范围广且成本低,其年消费量正在增加。TCs不能被人类和动物完全代谢。它们可能被滥用或过度使用,导致TCs在生态环境中持续积累,并对非目标生物产生潜在负面影响。这些TCs可能会扩散到食物链中,对人类健康和生态构成严重威胁。基于中国环境,全面总结了TCs在粪便、污水、污泥、土壤和水中的残留情况,以及空气的潜在传播能力。本文收集了中国环境中不同介质中TCs的浓度,有助于建立中国TC污染物数据库,并为未来污染物的监测和处理提供便利。

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本文引用的文献

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Antibiotics, antibiotic resistance and associated risk in natural springs from an agroecosystem environment.抗生素、抗生素耐药性与农业生态系统环境中天然泉水中的相关风险
Sci Total Environ. 2023 Jan 20;857(Pt 1):159202. doi: 10.1016/j.scitotenv.2022.159202. Epub 2022 Oct 5.
2
The impact of chlorination on the tetracycline sorption behavior of microplastics in aqueous solution.氯化作用对水溶液中微塑料四环素吸附行为的影响。
Sci Total Environ. 2022 Nov 25;849:157800. doi: 10.1016/j.scitotenv.2022.157800. Epub 2022 Aug 4.
3
The role of soil components in the sorption of tetracycline and heavy metals in soils.
革兰氏阴性土壤细菌对四环素暴露的早期转录后反应揭示了一个DUF1127基因意想不到的衰减机制。
RNA Biol. 2025 Jun 18. doi: 10.1080/15476286.2025.2521887.
4
The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers.总悬浮颗粒物的微生物群落及其对健康上班族呼吸道微生物群落的影响。
Ecotoxicol Environ Saf. 2025 Feb;291:117874. doi: 10.1016/j.ecoenv.2025.117874. Epub 2025 Feb 8.
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Mesoporous TiO@g-CN Nanostructure-Enhanced Photocatalytic Degradation of Tetracycline Under Full-Spectrum Sunlight.介孔TiO@g-CN纳米结构增强全光谱阳光下四环素的光催化降解
Molecules. 2024 Dec 18;29(24):5981. doi: 10.3390/molecules29245981.
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MOFs-based adsorbents for the removal of tetracycline from water and food samples.用于从水和食品样品中去除四环素的基于金属有机框架材料的吸附剂。
Sci Rep. 2025 Jan 2;15(1):502. doi: 10.1038/s41598-024-84122-8.
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Polymers (Basel). 2024 Oct 20;16(20):2938. doi: 10.3390/polym16202938.
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