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食用和药用植物中多种真菌毒素的污染及健康风险评估。

Contamination and Health Risk Assessment of Multiple Mycotoxins in Edible and Medicinal Plants.

机构信息

School of Life Science, Nanjing Normal University, Nanjing 210023, China.

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.

出版信息

Toxins (Basel). 2023 Mar 10;15(3):209. doi: 10.3390/toxins15030209.

Abstract

Edible and medicinal plants (EMPs) are widely used but are easily infected by harmful fungi which produce mycotoxins. Herein, 127 samples from 11 provinces were collected to investigate 15 mycotoxins based on geographic, demographic, processing, and risk characteristics. A total of 13 mycotoxins were detected, and aflatoxin B (0.5697.00 μg/kg), deoxynivalenol (9.411570.35 μg/kg), fumonisin B (8.251875.77 μg/kg), fumonisin B (2.74543.01 μg/kg), ochratoxin A (0.6219.30 μg/kg), and zearalenone (1.642376.58 μg/kg) occurred more frequently. Mycotoxin levels and species were significantly different by region, types of EMPs, and method of processing. The margin of exposure (MOE) values was well below the safe MOE (10,000). AFB exposure from Coix seed and malt consumption in China was of high health concern. The hazard Index (HI) method showed the range of 113.15~130.73% for malt, indicating a public health concern. In conclusion, EMPs should be concerned because of the cumulative effects of co-occurred mycotoxins, and safety management strategies should be developed in follow-up studies.

摘要

食用和药用植物(EMP)被广泛使用,但它们很容易受到产生霉菌毒素的有害真菌的感染。本研究基于地理、人口统计学、加工和风险特征,从 11 个省收集了 127 个样本,调查了 15 种霉菌毒素。共检测到 13 种霉菌毒素,黄曲霉毒素 B(0.5697.00μg/kg)、脱氧雪腐镰刀菌烯醇(9.411570.35μg/kg)、伏马菌素 B(8.251875.77μg/kg)、伏马菌素 B(2.74543.01μg/kg)、赭曲霉毒素 A(0.6219.30μg/kg)和玉米赤霉烯酮(1.642376.58μg/kg)更为常见。霉菌毒素水平和种类因地区、EMP 类型和加工方法的不同而有显著差异。暴露边际(MOE)值远低于安全 MOE(10,000)。中国的薏苡仁和麦芽中 AFB 的暴露量令人高度关注健康问题。危害指数(HI)方法表明麦芽的范围为 113.15%~130.73%,表明存在公共卫生问题。总之,由于共存霉菌毒素的累积效应,应关注 EMPs,并应在后续研究中制定安全管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc96/10056361/ead7923f2846/toxins-15-00209-g001.jpg

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