Duncan M J, Banister M J, Reppert S M
Brain Res. 1986 Mar 26;369(1-2):326-30. doi: 10.1016/0006-8993(86)90544-5.
Previous studies show that the developing circadian system is entrained by a maternal signal during the prenatal and early postnatal period. The present study investigated the developmental onset of retina-mediated, light-dark entrainment. Juvenile rats were exposed to phase-shifts in the light-dark cycle at different ages and the pineal N-acetyltransferase rhythm was monitored on postnatal day 10. The results show that retina-mediated, light-dark entrainment begins by postnatal day 6 and overrides maternal entrainment by postnatal day 8.
先前的研究表明，发育中的昼夜节律系统在产前和产后早期受到母体信号的调节。本研究调查了视网膜介导的明暗调节的发育起始时间。将幼年大鼠在不同年龄暴露于明暗周期的相移中，并在出生后第10天监测松果体N-乙酰转移酶节律。结果表明，视网膜介导的明暗调节在出生后第6天开始，并在出生后第8天取代母体调节。
