Galgano Michela, Pellegrini Francesco, Fracchiolla Giuseppe, Mrenoshki Daniela, Zarea Aya Attia Koraney, Bianco Angelica, Del Sambro Laura, Capozzi Loredana, Schiavone Antonella, Saleh Medhat S, Camero Michele, Tempesta Maria, Cirone Francesco, Buonavoglia Domenico, Pratelli Annamaria, Buonavoglia Alessio
Department of Veterinary Medicine, University Aldo Moro of Bari, Sp Casamassima Km 3, Valenzano, 70010 Bari, Italy.
Department of Pharmacy-Drug Sciences, University Aldo Moro of Bari, Via Orabona 4, 70125 Bari, Italy.
Antibiotics (Basel). 2023 Feb 22;12(3):436. doi: 10.3390/antibiotics12030436.
The indiscriminate use of antimicrobials in poultry farms is linked to the increase in multi-resistant bacteria. Accordingly, based on the antimicrobial properties of Thyme Essential Oil (TEO), the present study evaluated the effects of TEO on the reduction of common microbial contaminants and on poultry litter. A litter bulk sample was collected in a broiler farm and qualitative/quantitative investigations identified and The experimental contamination with Derby wild strain was also performed. All pathogens showed phenotypic and genotypic resistance to different classes of antibiotics. The litter, split in different units, was treated with aqueous solutions of TEO at different concentrations (5% to 1.25%), demonstrating its effectiveness in reducing the total number of bacteria. The strongest antibacterial action was observed at the lowest concentration against , with a growth reduction compared to the positive control of 73.3% and 77.8% against and Derby, respectively, while towards . the reduction was 50%. Our data confirm the antimicrobial activity of TEO and suggest its possible application for the treatment of poultry litter as an effective and natural approach for the prevention of diseases caused by the most common bacteria that colonize poultry farms, counteracting the onset of antibiotic resistance.
家禽养殖场中抗菌药物的滥用与多重耐药菌的增加有关。因此，基于百里香精油（TEO）的抗菌特性，本研究评估了TEO对减少常见微生物污染物以及对家禽垫料的影响。在一个肉鸡养殖场收集了一份垫料大量样本，通过定性/定量调查确定了……还对德比野生菌株进行了实验性污染。所有病原体对不同类别的抗生素均表现出表型和基因型抗性。将垫料分成不同单元，用不同浓度（5%至1.25%）的TEO水溶液进行处理，结果表明其在减少细菌总数方面具有有效性。在最低浓度下对……观察到最强的抗菌作用，与阳性对照相比，对……和德比的生长减少分别为73.3%和77.8%，而对……减少为50%。我们的数据证实了TEO的抗菌活性，并表明其可能作为一种有效且天然的方法用于处理家禽垫料，以预防由在家禽养殖场定植的最常见细菌引起的疾病，对抗抗生素耐药性的产生。
