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可食用海藻提取物:健康状况下的特性及功能特性

Edible Seaweeds Extracts: Characterization and Functional Properties for Health Conditions.

作者信息

Coelho Mariana, Duarte Ana Patrícia, Pinto Sofia, Botelho Hugo M, Reis Catarina Pinto, Serralheiro Maria Luísa, Pacheco Rita

机构信息

Departamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa (ISEL), Av. Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal.

BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, Universidade de Lisboa, 1749-016 Lisboa, Portugal.

出版信息

Antioxidants (Basel). 2023 Mar 10;12(3):684. doi: 10.3390/antiox12030684.

Abstract

Seaweeds are popular foods due to claimed beneficial health effects, but for many there is a lack of scientific evidence. In this study, extracts of the edible seaweeds Aramé, Nori, and Fucus are compared. Our approach intends to clarify similarities and differences in the health properties of these seaweeds, thus contributing to target potential applications for each. Additionally, although Aramé and Fucus seaweeds are highly explored, information on Nori composition and bioactivities is scarce. The aqueous extracts of the seaweeds were obtained by decoction, then fractionated and characterized according to their composition and biological activity. It was recognized that fractioning the extracts led to bioactivity reduction, suggesting a loss of bioactive compounds synergies. The Aramé extract showed the highest antioxidant activity and Nori exhibited the highest potential for acetylcholinesterase inhibition. The identification of the bioactive compounds in the extracts allowed to see that these contained a mixture of phloroglucinol polymers, and it was suggested that Nori's effect on acetylcholinesterase inhibition may be associated with a smaller sized phlorotannins capable of entering the enzyme active site. Overall, these results suggest a promising potential for the use of these seaweed extracts, mainly Aramé and Nori, in health improvement and management of diseases, namely those associated to oxidative stress and neurodegeneration.

摘要

海藻因其宣称的有益健康功效而成为受欢迎的食物,但对许多海藻来说,缺乏科学证据。在本研究中,对可食用海藻阿拉姆(Aramé)、紫菜(Nori)和墨角藻(Fucus)的提取物进行了比较。我们的方法旨在阐明这些海藻健康特性的异同,从而有助于确定每种海藻的潜在应用目标。此外,尽管对阿拉姆和墨角藻海藻进行了大量研究,但关于紫菜成分和生物活性的信息却很少。通过煎煮获得海藻的水提取物,然后根据其组成和生物活性进行分级和表征。人们认识到,对提取物进行分级会导致生物活性降低,这表明生物活性化合物的协同作用丧失。阿拉姆提取物显示出最高的抗氧化活性,紫菜表现出最高的乙酰胆碱酯酶抑制潜力。对提取物中生物活性化合物的鉴定表明,这些提取物含有间苯三酚聚合物的混合物,并且有人提出紫菜对乙酰胆碱酯酶抑制的作用可能与能够进入酶活性位点的较小尺寸的间苯三酚单宁有关。总体而言,这些结果表明这些海藻提取物,主要是阿拉姆和紫菜,在改善健康和管理疾病,即与氧化应激和神经退行性变相关的疾病方面具有广阔的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba51/10045430/3ed0c098a4a9/antioxidants-12-00684-g001.jpg

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