Tamás Bender, Gabriella Kalics, Kristóf Árvai, Anett Illés, János Pál Kósa, Bálint Tobiás, Péter Lakatos, Márton Papp, Katalin Nemes
Polyclinic of the Hospitaller Brothers of St John of God, Árpád Fejedelem Útja 7, H-1023 Budapest, Hungary.
Ligetszépe Health Center, Folk College Foundation of Lakitelek, H-6065 Lakitelek, Hungary.
Life (Basel). 2023 Mar 9;13(3):746. doi: 10.3390/life13030746.
The beneficial effects of balneotherapy have been proven by numerous clinical studies on locomotor disorders. To date, there is only scant data on changes in the microbiome system of the skin during balneotherapy. The aim of this study was to compare the effects of thermal water and tap water on the skin's microbiome in healthy volunteers. 30 healthy female volunteers participated in the study. The experimental group (of 15 women) spent 30-min 10 times, in Gabriella Spring's thermal baths (i.e., mineral water containing sodium hydrogen carbonate).The controlled group (15 women) had the same, but in tap water. The results of this study have proven that there is a difference in the influencing effects of tap water and medicinal water on the microbiome of the skin. After bathing in the thermal water of Lakitelek, increased significantly at the genus level, and the tendency for bacteria also increased. At the species level, increased significantly, while and the tendency for decreased. When the values of the two trial groups after bathing at the genus level were compared, increased significantly, while tended to increase, tended to decrease, tended to increase significantly, and tended to decrease. At the species level, decreased significantly, and the tendency for decreased. The growth of and the decrease in the tendency of , and confirm the beneficial effect of balneotherapy. In this study, trends are represented by the uncorrected value. The main result was that the thermal water changed certain bacteria of the skin, both on the genus and species levels, but there were no significant changes in the tap water used, either at the genus or species level. We first compared the worlds of thermal water and tap water's microbiome systems. The thermal water decreased the number of certain inflammatory infectious agents and could enhance some of their positive effects, which have been proven at the molecular level. Our results can provide an important clue in the treatment of certain skin diseases. The research of the skin microbiome during balneotherapy can be one of the most intriguing and exciting topics of the future and can bring us closer to understanding the mechanism of action of balneotherapy.
众多关于运动障碍的临床研究已证实了浴疗法的有益效果。迄今为止，关于浴疗法期间皮肤微生物系统变化的数据极少。本研究的目的是比较热水和自来水对健康志愿者皮肤微生物群的影响。30名健康女性志愿者参与了该研究。实验组（15名女性）在加布里埃拉温泉浴场（即含有碳酸氢钠的矿泉水）中浸泡10次，每次30分钟。对照组（15名女性）进行相同操作，但使用的是自来水。本研究结果证明，自来水和药用水对皮肤微生物群的影响存在差异。在拉基泰莱克温泉水中沐浴后，属水平上 显著增加， 细菌的趋势也增加。在种水平上， 显著增加，而 和 的趋势下降。比较两个试验组沐浴后属水平的数值时， 显著增加， 有增加趋势， 有下降趋势， 显著增加趋势， 有下降趋势。在种水平上， 显著下降， 趋势下降。 和 的减少趋势以及 的增加趋势证实了浴疗法的有益效果。在本研究中，趋势由未校正的 值表示。主要结果是，热水在属和种水平上都改变了皮肤的某些细菌，但所用自来水在属或种水平上均无显著变化。我们首次比较了热水和自来水的微生物系统。热水减少了某些炎性感染因子的数量，并能增强它们的一些积极作用，这已在分子水平上得到证实。我们的结果可为某些皮肤病的治疗提供重要线索。浴疗法期间皮肤微生物群的研究可能是未来最有趣和令人兴奋的课题之一，能让我们更接近理解浴疗法的作用机制。
