Tan Jinyi, Zhao Haikun, Li Josh, Gong Yihan, Li Xin
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Department of Botany, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Pathogens. 2023 Feb 26;12(3):379. doi: 10.3390/pathogens12030379.
is one of the most devastating pathogenic fungi that affects a wide range of cereal plants, especially rice. Rice blast disease causes substantial economic losses around the globe. The genome was first sequenced at the beginning of this century and was recently updated with improved annotation and completeness. In this review, key molecular findings on the fungal development and pathogenicity mechanisms of are summarized, focusing on fully characterized genes based on mutant analysis. These include genes involved in the various biological processes of this pathogen, such as vegetative growth, conidia development, appressoria formation and penetration, and pathogenicity. In addition, our syntheses also highlight gaps in our current understanding of development and virulence. We hope this review will serve to improve a comprehensive understanding of and assist disease control strategy designs in the future.
是最具破坏性的致病真菌之一，可影响多种谷类植物，尤其是水稻。稻瘟病在全球范围内造成重大经济损失。该真菌的基因组于本世纪初首次测序，最近进行了更新，注释和完整性得到了改进。在本综述中，总结了关于该真菌发育和致病机制的关键分子研究结果，重点关注基于突变分析充分表征的基因。这些基因包括参与该病原体各种生物学过程的基因，如营养生长、分生孢子发育、附着胞形成和穿透以及致病性。此外，我们的综述还突出了目前对该真菌发育和毒力理解上的差距。我们希望本综述有助于增进对该真菌的全面理解，并为未来的病害控制策略设计提供帮助。
