Zhang Yuhang, Poon Kingsley, Masonsong Gweneth Sofia P, Ramaswamy Yogambha, Singh Gurvinder
School of Biomedical Engineering, The University of Sydney, Camperdown, NSW 2008, Australia.
Sydney Nano Institute, The University of Sydney, Camperdown, NSW 2008, Australia.
Pharmaceutics. 2023 Mar 12;15(3):922. doi: 10.3390/pharmaceutics15030922.
Significant progress in nanotechnology has enormously contributed to the design and development of innovative products that have transformed societal challenges related to energy, information technology, the environment, and health. A large portion of the nanomaterials developed for such applications is currently highly dependent on energy-intensive manufacturing processes and non-renewable resources. In addition, there is a considerable lag between the rapid growth in the innovation/discovery of such unsustainable nanomaterials and their effects on the environment, human health, and climate in the long term. Therefore, there is an urgent need to design nanomaterials sustainably using renewable and natural resources with minimal impact on society. Integrating sustainability with nanotechnology can support the manufacturing of sustainable nanomaterials with optimized performance. This short review discusses challenges and a framework for designing high-performance sustainable nanomaterials. We briefly summarize the recent advances in producing sustainable nanomaterials from sustainable and natural resources and their use for various biomedical applications such as biosensing, bioimaging, drug delivery, and tissue engineering. Additionally, we provide future perspectives into the design guidelines for fabricating high-performance sustainable nanomaterials for medical applications.
纳米技术的重大进展极大地推动了创新产品的设计与开发,这些产品改变了与能源、信息技术、环境和健康相关的社会挑战。目前,为这类应用开发的大部分纳米材料高度依赖能源密集型制造工艺和不可再生资源。此外,这类不可持续的纳米材料在创新/发现方面的快速增长与其对环境、人类健康和气候的长期影响之间存在相当大的滞后。因此,迫切需要利用可再生和自然资源以对社会影响最小的方式可持续地设计纳米材料。将可持续性与纳米技术相结合可以支持制造具有优化性能的可持续纳米材料。这篇简短综述讨论了设计高性能可持续纳米材料的挑战和框架。我们简要总结了利用可持续和自然资源生产可持续纳米材料及其在生物传感、生物成像、药物递送和组织工程等各种生物医学应用中的近期进展。此外,我们还展望了用于医疗应用的高性能可持续纳米材料制造的设计指南。